{"id":"W4210656005","doi":"10.1093/carcin/bgac015","title":"Wild-type p53 suppresses formin-binding protein-17 (FBP17) to reduce invasion","year":2022,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Formins; Wild type; P53 protein; Biology; Plasma protein binding; Binding protein; Binding site; Cell biology; Cancer research; Genetics; Mutant; Gene; Cytoskeleton; Actin cytoskeleton; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002796524,0.0002626565,0.0004037058,0.0003597874,0.0003967958,0.0000251683,0.000273422,0.0001010136,0.0009194172],"category_scores_gemma":[0.0002588802,0.0002774775,0.000177687,0.001029465,0.00003917719,0.00007024385,0.0004206032,0.0003094291,0.000119654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005965084,"about_ca_system_score_gemma":0.0004911046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001372461,"about_ca_topic_score_gemma":0.00001693507,"domain_scores_codex":[0.997762,0.00009063466,0.0003451889,0.0006095552,0.0006738806,0.0005187068],"domain_scores_gemma":[0.9985703,0.00003673462,0.0001044219,0.0007844404,0.0001668937,0.0003371989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00051193,0.0001008974,0.001732284,0.00009768866,0.00007163431,0.0002822312,0.0004660425,0.0002611752,0.9747979,0.00003719195,0.01731814,0.004322889],"study_design_scores_gemma":[0.00113212,0.0008806925,0.001717502,0.000124053,0.0002019233,0.0003216634,0.0004997905,0.00004288129,0.9164466,0.00001719519,0.07828117,0.0003344214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929439,0.001341977,0.00005459325,0.001241662,0.000606222,0.001592411,0.00005561178,0.0001644818,0.001999119],"genre_scores_gemma":[0.9924499,0.00002841141,0.0007580642,0.0006817804,0.0002168489,0.000451243,0.0001021414,0.0001016994,0.005209947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06096303,"threshold_uncertainty_score":0.9999939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03312860579078288,"score_gpt":0.2689782054812003,"score_spread":0.2358495996904175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}