{"id":"W4210666168","doi":"10.1101/2022.01.26.477857","title":"An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Alliance for Research on Schizophrenia and Depression; McGill University; Tulane University; Brain and Behavior Research Foundation","keywords":"Neuroscience; Long-term potentiation; Synaptic plasticity; AMPA receptor; Postsynaptic potential; Biology; Neuroplasticity; Hippocampus; Metaplasticity; Synapse; Gating; Glutamate receptor; Receptor; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009822811,0.0002072905,0.0002043909,0.0001956803,0.00009894673,0.0001802614,0.0001502171,0.0001982628,0.001263355],"category_scores_gemma":[0.0001074101,0.00007847448,0.0001977618,0.0000904016,0.0001514713,0.0001618119,0.0001886362,0.0002717442,0.000321148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002240614,"about_ca_system_score_gemma":0.00008523816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004874725,"about_ca_topic_score_gemma":0.0004902665,"domain_scores_codex":[0.9999373,0.000007870059,0.000005902851,0.0000155919,0.00001453288,0.00001871716],"domain_scores_gemma":[0.9999188,0.000005427892,0.00003206874,0.000007069684,0.0000100115,0.00002660829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003044651,0.00001185072,0.000959026,0.00001935146,0.000005386322,0.00010881,0.000008273851,0.00002579994,0.997521,0.00003542782,0.00004505321,0.0009556968],"study_design_scores_gemma":[0.00003200527,0.0005476768,0.1090246,0.00001390186,0.00004601969,0.0008139537,0.0000843134,0.001237708,0.8850722,0.0002517292,0.002862252,0.00001372012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996345,0.001242152,0.001005135,0.0000827665,0.00003914522,0.000007146676,0.0005238302,0.00002950407,0.000725266],"genre_scores_gemma":[0.9955229,0.0005402417,0.0009298147,0.00006416241,0.00001195816,0.00002211917,0.0004652779,0.00001480234,0.00242866],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001263355,"threshold_uncertainty_score":0.004226327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009599172167674969,"score_gpt":0.2194814543655886,"score_spread":0.2098822821979136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}