{"id":"W4210670825","doi":"10.1002/alz.054930","title":"Data‐driven staging and subtyping of genetic frontotemporal dementia using multi‐modal MRI","year":2021,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Frontotemporal dementia; Neuroimaging; Subtyping; Dementia; Neuropsychology; Medicine; Disease; Modalities; Psychology; Clinical psychology; Audiology; Pathology; Psychiatry; Cognition; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001462824,0.0003898617,0.0003418944,0.002614317,0.0002338473,0.0006538869,0.0004837474,0.0004364991,0.0005819752],"category_scores_gemma":[0.004230069,0.0001520532,0.0005263794,0.0006993121,0.0001964818,0.0002639949,0.0005731267,0.0003664203,0.0001566397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004730832,"about_ca_system_score_gemma":0.0004033485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004415765,"about_ca_topic_score_gemma":0.006703749,"domain_scores_codex":[0.9996204,0.0001606737,0.00003684713,0.0001039675,0.00004469308,0.00003339364],"domain_scores_gemma":[0.9984255,0.0006634422,0.0003260994,0.0002117849,0.0002650795,0.0001080818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001141758,0.0002817856,0.8071936,0.0001294845,0.0006006426,0.0003948709,0.0002524849,0.04291444,0.03830275,0.0005655863,0.001428777,0.1067938],"study_design_scores_gemma":[0.00003884508,0.0001895572,0.3819729,0.00003970305,0.0001691741,0.0006652077,0.0001678678,0.5993817,0.01416046,0.002382196,0.0007779633,0.00005427329],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9497253,0.0002226158,0.04703718,0.0001348638,0.00001184895,0.00006189605,0.002100363,0.0002982104,0.0004077122],"genre_scores_gemma":[0.9695285,0.000044601,0.02849234,0.00002326389,0.00001282241,0.00004917784,0.001673118,0.0000211987,0.0001550277],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004415765,"threshold_uncertainty_score":0.008780122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04594236952174848,"score_gpt":0.3005319706045471,"score_spread":0.2545896010827986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}