{"id":"W4210671238","doi":"10.1080/13816810.2022.2025608","title":"Lessons learned from research on choroideremia","year":2022,"lang":"en","type":"article","venue":"Ophthalmic Genetics","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Foundation Fighting Blindness; Choroideremia Research Foundation","keywords":"Choroideremia; Clinical trial; Medicine; Harm; Alternative medicine; Genetic enhancement; Family medicine; Psychology; Internal medicine; Ophthalmology; Pathology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000364562,0.0001365139,0.0001045208,0.00007788605,0.0003928053,0.00003239432,0.0004286906,0.00008414671,0.0005262254],"category_scores_gemma":[0.00005927612,0.0001495575,0.00006524367,0.0001880576,0.00007469123,9.728961e-7,0.0004706691,0.0003075854,0.0001020442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003926946,"about_ca_system_score_gemma":0.0001580865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004328912,"about_ca_topic_score_gemma":0.000006620577,"domain_scores_codex":[0.9983011,0.0002262456,0.0001585978,0.0004944871,0.000460133,0.0003594468],"domain_scores_gemma":[0.9992965,0.00003431951,0.00004148069,0.0004771737,0.00006260283,0.00008794095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006381223,0.0004195598,0.01381479,0.00001388778,0.0001291443,0.00007800973,0.0003535186,0.005393919,0.8610649,0.0004735347,0.07276675,0.04485385],"study_design_scores_gemma":[0.001411494,0.001529702,0.03369429,0.00001218513,0.00001693112,0.00004509823,0.002112507,0.000172069,0.1501275,0.006077277,0.8041178,0.0006831878],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9741858,0.001140709,0.00003187363,0.001238138,0.0002306656,0.000156377,0.00004611004,0.00001018319,0.02296019],"genre_scores_gemma":[0.9918993,0.0005085759,0.0005853525,0.0002304827,0.000139028,0.00006593388,0.0003742171,0.00003487534,0.006162194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.731351,"threshold_uncertainty_score":0.6098776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1655641362185687,"score_gpt":0.4000309905553692,"score_spread":0.2344668543368006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}