{"id":"W4210671238","doi":"10.1080/13816810.2022.2025608","title":"Lessons learned from research on choroideremia","year":2022,"lang":"en","type":"article","venue":"Ophthalmic Genetics","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Foundation Fighting Blindness; Choroideremia Research Foundation","keywords":"Choroideremia; Clinical trial; Medicine; Harm; Alternative medicine; Genetic enhancement; Family medicine; Psychology; Internal medicine; Ophthalmology; Pathology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.05639181,0.001368166,0.002178335,0.00255526,0.002387971,0.00697863,0.003033181,0.008529152,0.005588237],"category_scores_gemma":[0.07966213,0.0007509846,0.00198779,0.001492325,0.01302053,0.01364871,0.004406175,0.02414986,0.002166566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005189787,"about_ca_system_score_gemma":0.009192486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004998546,"about_ca_topic_score_gemma":0.008004528,"domain_scores_codex":[0.9795368,0.01221309,0.001478615,0.001920064,0.003929202,0.0009221982],"domain_scores_gemma":[0.8682278,0.09831034,0.002318085,0.006336797,0.01565819,0.00914871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004640693,0.0004971205,0.005160813,0.006785388,0.0004202361,0.002521361,0.00804875,0.001211286,0.001239537,0.08311294,0.51154,0.3789986],"study_design_scores_gemma":[0.0002683073,0.0006350034,0.002598379,0.01041327,0.0002058799,0.003060023,0.006734071,0.0005195948,0.001734809,0.2861928,0.687413,0.0002248515],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.002839382,0.2349869,0.007043728,0.7308721,0.0155777,0.00006722457,0.000147882,0.0001660872,0.008298942],"genre_scores_gemma":[0.06957126,0.4002461,0.03014436,0.4421301,0.04583162,0.0004339705,0.000223034,0.0003359466,0.01108352],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.05639181,"threshold_uncertainty_score":0.298232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1655641362185687,"score_gpt":0.4000309905553692,"score_spread":0.2344668543368006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}