{"id":"W4210751967","doi":"10.1016/j.xops.2022.100118","title":"Systemic Complement Activation Profiles in Nonexudative Age-Related Macular Degeneration","year":2022,"lang":"en","type":"article","venue":"Ophthalmology Science","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Eye Institute; National Institutes of Health; American Macular Degeneration Foundation","keywords":"Macular degeneration; Complement system; Medicine; Geographic atrophy; Complement (music); Immunology; Antibody; Biology; Ophthalmology; Phenotype; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003118387,0.00007839793,0.0001352403,0.000186651,0.0002768439,0.00001130048,0.0001082668,0.00001845196,0.0004668199],"category_scores_gemma":[0.00004035613,0.00006921032,0.00002817415,0.0006202625,0.0001843382,0.00009880101,0.00009482195,0.000100679,0.00001832762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003828193,"about_ca_system_score_gemma":0.0001897347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009710398,"about_ca_topic_score_gemma":4.397216e-7,"domain_scores_codex":[0.9988791,0.00009967629,0.0001839231,0.0003056036,0.0003331492,0.0001985501],"domain_scores_gemma":[0.9996299,0.00002019413,0.00008210352,0.0001559758,0.00004986141,0.00006200105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003332797,0.0009270861,0.6423417,0.00005449259,0.00004790858,0.003480377,0.0008403002,0.002435937,0.3430333,0.005435202,0.00007232392,0.0009980424],"study_design_scores_gemma":[0.001616187,0.001020834,0.9775054,0.00005747233,0.00003652365,0.003418837,0.0007962877,0.003597799,0.01118169,0.0006033282,0.00003314694,0.0001325217],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955773,0.00007923778,0.00001956982,0.0002752161,0.0001166119,0.0006215541,0.00001044939,0.00001262871,0.00328748],"genre_scores_gemma":[0.9989449,0.000001908244,0.0002846621,0.00004892744,0.000008607,0.0001919847,0.0001282774,0.000005139891,0.0003856214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3351636,"threshold_uncertainty_score":0.511135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03562792465275605,"score_gpt":0.3370869509337351,"score_spread":0.3014590262809791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}