{"id":"W4210773514","doi":"10.1002/syn.22224","title":"Endosomal recycling and dopamine neurotransmission: Exploring the links between the retromer and Parkinson's disease","year":2022,"lang":"en","type":"review","venue":"Synapse","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Retromer; Dopamine; Endosome; Neurotransmission; Dopamine transporter; Neuroscience; Dopamine Plasma Membrane Transport Proteins; Dopaminergic; Biology; Cell biology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000420105,0.0008147629,0.001017888,0.002684464,0.000263688,0.0009531144,0.0006802453,0.001210199,0.002371976],"category_scores_gemma":[0.0005217086,0.0002286645,0.0003339635,0.003246489,0.0004666245,0.001481072,0.0008106952,0.001541198,0.001641714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005653891,"about_ca_system_score_gemma":0.000927871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009023895,"about_ca_topic_score_gemma":0.001314049,"domain_scores_codex":[0.9998863,0.00002034793,0.00001760506,0.00002226584,0.00004093326,0.00001260995],"domain_scores_gemma":[0.9997832,0.00009960524,0.00003532146,0.000006255274,0.00004894456,0.00002664414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007175002,0.00005981034,0.0002067338,0.01466299,0.00007667526,0.0004270054,0.00009710426,0.0003686488,0.001993897,0.004665645,0.02211421,0.9552554],"study_design_scores_gemma":[0.00001208882,0.0001094297,0.001184015,0.004837622,0.000128201,0.003524465,0.0001095469,0.0001076405,0.000501309,0.002724368,0.9867409,0.00002045449],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006562372,0.9991969,0.00006841349,0.0001449794,0.00008793979,0.000001210339,0.000005160904,0.000003215401,0.0004265907],"genre_scores_gemma":[0.0003807884,0.9990402,0.0001059268,0.00009181845,0.0001071442,0.000002258782,0.00001211911,8.008295e-7,0.0002588309],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002684464,"threshold_uncertainty_score":0.007935047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05963273907079006,"score_gpt":0.2741832562638039,"score_spread":0.2145505171930138,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}