{"id":"W4210792895","doi":"10.1016/j.fhfh.2022.100054","title":"Recent advances in lipid-protein conjugate-based delivery systems in nutraceutical, drug, and gene delivery","year":2022,"lang":"en","type":"article","venue":"Food Hydrocolloids for Health","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nutraceutical; Solid lipid nanoparticle; Bioavailability; Drug delivery; Gene delivery; Conjugate; Chemistry; Delivery system; Nanotechnology; Pharmacology; Biotechnology; Biochemistry; Materials science; Biology; Genetic enhancement; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006397228,0.0002261064,0.0003557428,0.000182602,0.0002141013,0.00002768827,0.0002276467,0.00009892513,0.00001142019],"category_scores_gemma":[0.0000232067,0.0002501235,0.0000730918,0.0002281676,0.00006060042,0.00001408,0.000138475,0.0002136755,0.000001996526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000193096,"about_ca_system_score_gemma":0.0004922092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002379066,"about_ca_topic_score_gemma":0.001759594,"domain_scores_codex":[0.9978907,0.0002280503,0.0005421095,0.0005960389,0.0001927188,0.000550455],"domain_scores_gemma":[0.9993179,0.0000345174,0.0001540538,0.000277054,0.00006141953,0.0001550875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01347574,0.003387037,0.0172342,0.00297428,0.0002400821,0.00005083902,0.001362416,0.06590521,0.7888909,0.0006635701,0.009621357,0.09619438],"study_design_scores_gemma":[0.00935681,0.01382274,0.00086913,0.0003177406,0.00002130955,0.0000325686,0.002361953,0.009386061,0.1019651,0.0002154284,0.8605183,0.001132803],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9468671,0.04975567,0.0001088202,0.0006818639,0.0002447156,0.002040701,0.0002388688,0.00001476181,0.00004749548],"genre_scores_gemma":[0.989363,0.006938796,0.0002380595,0.00127901,0.0001169504,0.001687481,0.000230681,0.00003273264,0.0001132662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.850897,"threshold_uncertainty_score":0.9999951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01554740676843786,"score_gpt":0.2797922917978414,"score_spread":0.2642448850294035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}