{"id":"W4210794959","doi":"10.1016/j.jtct.2022.01.024","title":"Real-World Eligibility for Second-Line Chimeric Antigen Receptor T Cell Therapy in Large B Cell Lymphoma: A Population-Based Analysis","year":2022,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; Alberta Health Services","funders":"","keywords":"Medicine; Chemoimmunotherapy; Population; Oncology; Internal medicine; Autologous stem-cell transplantation; Chimeric antigen receptor; Transplantation; Lymphoma; Surgery; Rituximab; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004106008,0.000319294,0.0007010641,0.001242503,0.0004777206,0.001628683,0.001073628,0.001296785,0.002641468],"category_scores_gemma":[0.01310895,0.0003145435,0.001098771,0.001554907,0.0007945934,0.001473052,0.001174333,0.001238013,0.0006685402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008897523,"about_ca_system_score_gemma":0.0003961157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003062246,"about_ca_topic_score_gemma":0.0032082,"domain_scores_codex":[0.995517,0.002263561,0.0003451813,0.000973616,0.0004459433,0.0004546245],"domain_scores_gemma":[0.9836369,0.007275123,0.00613768,0.0009624765,0.0009666171,0.001021218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001175968,0.0001227867,0.9943814,0.00002153788,0.0003782071,0.00009460017,0.0001218882,0.00063014,0.000200919,0.0001068691,0.000425899,0.002339842],"study_design_scores_gemma":[0.00005635439,0.0006283686,0.9931717,0.00001333517,0.0002581806,0.000521065,0.0006576406,0.003480948,0.0001359921,0.0001807952,0.0008640644,0.00003157212],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997747,0.0002186061,0.0003304381,0.00007285747,0.000005836766,0.00002087561,0.001159448,0.000008237968,0.0004367853],"genre_scores_gemma":[0.9986683,0.00004999857,0.00009154318,0.00003802363,0.000007009343,0.00001954028,0.001024077,0.000007570586,0.00009389961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004106008,"threshold_uncertainty_score":0.02171493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02426722053036806,"score_gpt":0.3147742005841869,"score_spread":0.2905069800538188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}