{"id":"W4210805203","doi":"10.1128/mbio.02920-21","title":"Structure of the Core Postfusion Porcine Endogenous Retrovirus Fusion Protein","year":2022,"lang":"en","type":"article","venue":"mBio","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Canada Research Chairs; Government of Canada; Canada Foundation for Innovation; U.S. Department of Energy","keywords":"Virology; Endogeny; Retrovirus; Fusion protein; Fusion; Core protein; Core (optical fiber); Endogenous retrovirus; Biology; Computational biology; Cell biology; Virus; Recombinant DNA; Computer science; Gene; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006777743,0.0001903271,0.0001543771,0.0002826055,0.0002062879,0.0002941789,0.0002417755,0.0002753657,0.0006320002],"category_scores_gemma":[0.0001793063,0.0001021401,0.0002439489,0.0004026537,0.0001922176,0.0002794722,0.0001138267,0.0003824127,0.0002577112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005894984,"about_ca_system_score_gemma":0.0002898738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001927129,"about_ca_topic_score_gemma":0.001275781,"domain_scores_codex":[0.9999574,0.000005078875,0.000002313555,0.00001320396,0.00001148827,0.00001059047],"domain_scores_gemma":[0.9998853,0.00001867963,0.0000392416,0.000007944089,0.00002143597,0.00002736726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003801341,0.00005594621,0.004260636,0.00008864609,0.00002798699,0.0005267791,0.0001828872,0.00233027,0.9845027,0.00165517,0.0002488767,0.005740004],"study_design_scores_gemma":[0.00007459414,0.001690776,0.1575553,0.00006630283,0.0002334091,0.002347171,0.0008504863,0.08744516,0.7212194,0.002469673,0.02593647,0.0001112315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933506,0.0008178273,0.003334054,0.00009039384,0.00001560121,0.00001630151,0.0002955083,0.00003542035,0.002044329],"genre_scores_gemma":[0.9936929,0.0005580698,0.002866552,0.00006268056,0.000008727154,0.00001076199,0.001483632,0.0000166238,0.001300041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001927129,"threshold_uncertainty_score":0.00427717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0214446235946128,"score_gpt":0.258973182659967,"score_spread":0.2375285590653542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}