{"id":"W4210829474","doi":"10.1080/10428194.2022.2030477","title":"Pomalidomide, dexamethasone, and daratumumab immediately after lenalidomide-based treatment in patients with multiple myeloma: updated efficacy, safety, and health-related quality of life results from the phase 2 MM-014 trial","year":2022,"lang":"en","type":"article","venue":"Leukemia & lymphoma/Leukemia and lymphoma","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Vancouver General Hospital; McGill University Health Centre","funders":"Bristol-Myers Squibb","keywords":"Lenalidomide; Pomalidomide; Medicine; Daratumumab; Dexamethasone; Multiple myeloma; Internal medicine; Neutropenia; Oncology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001595933,0.0005645087,0.001188974,0.0002714899,0.0002602648,0.0008259947,0.000489859,0.0005571109,0.001866992],"category_scores_gemma":[0.001362853,0.0002128058,0.00129017,0.0003848978,0.0002792194,0.0005821816,0.000363133,0.002245005,0.0003340734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005895399,"about_ca_system_score_gemma":0.0007237183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007601992,"about_ca_topic_score_gemma":0.002529959,"domain_scores_codex":[0.9994041,0.0003324409,0.00004075013,0.00007092311,0.00008805504,0.00006375162],"domain_scores_gemma":[0.9994161,0.0001327045,0.0002167283,0.00003569711,0.00003848516,0.0001602821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6913451,0.01075355,0.01704728,0.001535839,0.004979495,0.0001670347,0.0001522867,0.001849728,0.0076241,0.0003221075,0.007006851,0.2572166],"study_design_scores_gemma":[0.7312893,0.1716464,0.07306699,0.0004483788,0.004165326,0.0005563172,0.0001285665,0.001646992,0.002700594,0.0006125193,0.01367228,0.000066416],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9676782,0.02446412,0.0003353146,0.0009561207,0.0003471198,0.0008819056,0.001735698,0.00007807738,0.003523441],"genre_scores_gemma":[0.9815385,0.008823102,0.001300676,0.001359734,0.0003486918,0.0009364159,0.003953386,0.00001734942,0.001722094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001866992,"threshold_uncertainty_score":0.008440197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0279549313468648,"score_gpt":0.2923079348716945,"score_spread":0.2643530035248298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}