{"id":"W4210838359","doi":"10.1158/1055-9965.epi-21-1082","title":"Clinical Performance of the BD Onclarity Extended Genotyping Assay for the Management of Women Positive for Human Papillomavirus in Cervical Cancer Screening","year":2022,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Concordance; Genotyping; Triage; Cytology; Cervical intraepithelial neoplasia; Cervical cancer; Medicine; Genotype; Human papillomavirus; Positive predicative value; Gynecology; Viral load; Cervical cancer screening; Colposcopy; Cancer; Oncology; Internal medicine; Obstetrics; Virology; Pathology; Virus; Biology; Predictive value; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00331136,0.0002823507,0.0003051603,0.000570761,0.0002702552,0.000543159,0.0004034688,0.000376996,0.0007135934],"category_scores_gemma":[0.005815613,0.0001526313,0.0001525288,0.0004296926,0.0002336263,0.0001823543,0.0003598899,0.0002948939,0.000262507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001245578,"about_ca_system_score_gemma":0.001252118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02802019,"about_ca_topic_score_gemma":0.05452835,"domain_scores_codex":[0.9979419,0.0006412347,0.0001575051,0.0003487699,0.0007488211,0.0001616896],"domain_scores_gemma":[0.9975706,0.0007108997,0.0005080302,0.0001111674,0.0008839965,0.0002152606],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003080477,0.0001633261,0.9483162,0.00008855173,0.00009154058,0.00006567372,0.0003078856,0.0007552102,0.003237306,0.00005535288,0.001320947,0.04251745],"study_design_scores_gemma":[0.00008218058,0.00100282,0.9912305,0.00003049806,0.00006460123,0.0002749182,0.0001166732,0.00431741,0.001722984,0.00003431616,0.001105921,0.00001730651],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936618,0.00147102,0.001304359,0.0001160905,0.00002360266,0.0001435057,0.0004817107,0.00005209054,0.002745896],"genre_scores_gemma":[0.9972171,0.0001424051,0.00173691,0.00005838706,0.000006794597,0.00003975209,0.000450484,0.000002996183,0.000345183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02802019,"threshold_uncertainty_score":0.05571413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.135010435654546,"score_gpt":0.4687054266552594,"score_spread":0.3336949910007135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}