{"id":"W4210889103","doi":"10.1101/2022.02.06.478964","title":"Development of a Ribosome Profiling Protocol to Study Translation in the yeast <i>Kluyveromyces marxianus</i>","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Science Foundation Ireland; European Commission; Horizon 2020 Framework Programme; Wellcome Trust; McGill University","keywords":"Kluyveromyces marxianus; Ribosome profiling; Computational biology; Biology; Transcriptome; Gene expression profiling; Ribosome; Profiling (computer programming); RNA; Genome; Yeast; Gene; Gene expression; Genetics; Saccharomyces cerevisiae; Computer science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002124202,0.001798595,0.001638521,0.002088867,0.0008402918,0.0008109393,0.001134955,0.001035398,0.02741764],"category_scores_gemma":[0.002075882,0.001127934,0.001491044,0.001819415,0.0004976725,0.00073349,0.001083763,0.003342448,0.01379462],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005830373,"about_ca_system_score_gemma":0.001014365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007374121,"about_ca_topic_score_gemma":0.001658682,"domain_scores_codex":[0.9984514,0.000253966,0.0001512234,0.0004219341,0.0005011332,0.0002203734],"domain_scores_gemma":[0.9987691,0.0004645112,0.0001494681,0.0002146851,0.0003018671,0.0001003704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000807261,0.0001787288,0.0009664036,0.002441144,0.0001379435,0.0007156112,0.0002991976,0.002558153,0.8793464,0.004009648,0.04751444,0.06102502],"study_design_scores_gemma":[0.0002162559,0.0004338194,0.002304575,0.0002846541,0.0001152793,0.0004761217,0.00008975202,0.007624754,0.8495591,0.002100278,0.1366099,0.000185656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.06750287,0.003461821,0.7258569,0.0028323,0.002001314,0.00309867,0.1321427,0.04732745,0.01577603],"genre_scores_gemma":[0.131699,0.004371387,0.7212323,0.00190553,0.0002964144,0.01002737,0.1049057,0.006935275,0.01862702],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.02741764,"threshold_uncertainty_score":0.09172112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02477093883589475,"score_gpt":0.260008570749436,"score_spread":0.2352376319135413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}