{"id":"W4210893666","doi":"10.1016/j.vaccine.2021.12.060","title":"Cutaneous CpG adjuvant conditioning to enhance vaccine responses","year":2022,"lang":"en","type":"article","venue":"Vaccine","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Children's Hospital; SKiN Health; University of British Columbia","funders":"Canadian Institutes of Health Research; BC Children's Hospital","keywords":"Ovalbumin; Adjuvant; CpG Oligodeoxynucleotide; CpG site; Vaccination; Immunology; Medicine; Antigen; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003246452,0.0002063801,0.0003292319,0.0003497376,0.001032,0.00002036856,0.0003622684,0.00007414656,0.01862506],"category_scores_gemma":[0.0003015211,0.0002062307,0.0001023706,0.0005099116,0.000004997072,0.00007183796,0.00037909,0.00040848,0.001223122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001305797,"about_ca_system_score_gemma":0.00009779174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009808162,"about_ca_topic_score_gemma":0.00003077176,"domain_scores_codex":[0.9983386,0.00039879,0.0003924748,0.0003381752,0.00006342217,0.0004685477],"domain_scores_gemma":[0.9988724,0.0003986337,0.0001246444,0.0004699056,0.00009475681,0.00003967425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00507935,0.0003719993,0.002581988,0.00001402076,0.0002270792,0.0001202342,0.001023069,0.0005066551,0.831037,0.002549725,0.1428183,0.01367056],"study_design_scores_gemma":[0.001787233,0.001363037,0.01950975,0.00002226099,0.00006596416,0.002227812,0.001058527,0.00001487858,0.1340366,0.0002273115,0.8392436,0.0004430065],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987684,0.003544347,0.0005765321,0.00550071,0.001165935,0.0004498266,0.0002436167,0.00021345,0.0006215873],"genre_scores_gemma":[0.9530018,0.00004719229,0.0000852357,0.001126983,0.00004674494,0.0002846998,0.0002302052,0.00003288475,0.04514425],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6970003,"threshold_uncertainty_score":0.9995545,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008792448878559619,"score_gpt":0.2757150134260005,"score_spread":0.2669225645474408,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}