{"id":"W4210950866","doi":"10.1182/blood.2021014299","title":"Telomeres, aging, and cancer: the big picture","year":2022,"lang":"en","type":"article","venue":"Blood","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Terry Fox Research Institute","keywords":"Telomere; Biology; Context (archaeology); Genetics; Cancer; Senescence; Disease; Telomerase; Evolutionary biology; DNA; Medicine; Gene; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003735976,0.001046835,0.002209331,0.002347012,0.001702341,0.005403237,0.001627924,0.00454538,0.003794629],"category_scores_gemma":[0.003817933,0.0004338723,0.0008878816,0.002368444,0.004807744,0.01466073,0.003568998,0.01046214,0.0008055096],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001698326,"about_ca_system_score_gemma":0.002869642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00219848,"about_ca_topic_score_gemma":0.004425207,"domain_scores_codex":[0.9992187,0.0002134186,0.00008321455,0.0001397325,0.000256616,0.0000883008],"domain_scores_gemma":[0.9952998,0.00297822,0.0003234402,0.0002246106,0.0006113362,0.0005626557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009329041,0.0002408247,0.007433669,0.009286576,0.0005990185,0.001012773,0.002062423,0.00150247,0.004508976,0.1951037,0.1600609,0.6172557],"study_design_scores_gemma":[0.00006237235,0.0004675081,0.0137064,0.005789272,0.0004250475,0.001510412,0.00474175,0.0009858204,0.0007577984,0.4390993,0.5322886,0.0001657382],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001577483,0.9062769,0.001048182,0.08677491,0.002630063,0.000005234022,0.00007531707,0.00003040172,0.001581584],"genre_scores_gemma":[0.02216518,0.9378375,0.001184798,0.02585986,0.0113658,0.00002168951,0.00008436066,0.00002029177,0.001460468],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005403237,"threshold_uncertainty_score":0.01975799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01532761594304906,"score_gpt":0.2490442419186859,"score_spread":0.2337166259756368,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}