{"id":"W4211003614","doi":"10.1101/2022.02.09.22270754","title":"Glycomic Analysis Identifies Pre-Vaccination Markers of Response to Influenza Vaccine, Implicating the Complement Pathway","year":2022,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Vaccination; Glycosylation; Immunology; Influenza vaccine; Immune system; Glycan; Biology; Antigen; Antibody; Virology; Glycoprotein; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000160415,0.0001563782,0.0001858212,0.0003159278,0.0001541084,0.0003262896,0.00006352237,0.0002447141,0.001527044],"category_scores_gemma":[0.000215669,0.00006322058,0.0001825451,0.0002648593,0.00009498162,0.0001176504,0.0001784482,0.000249594,0.0003012292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001513222,"about_ca_system_score_gemma":0.0001173955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001650023,"about_ca_topic_score_gemma":0.001224444,"domain_scores_codex":[0.999935,0.00001012319,0.000003928187,0.00001555277,0.00001515882,0.00002018319],"domain_scores_gemma":[0.9999437,0.00001033999,0.00001386928,0.000004928221,0.00001364212,0.00001355684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009208334,0.00008458597,0.1335609,0.00006840521,0.00007821946,0.0001339405,0.0001302537,0.0001723735,0.8538553,0.0001379809,0.000538487,0.01031872],"study_design_scores_gemma":[0.000006660954,0.0003241563,0.9232897,0.000009644377,0.00003821675,0.000371269,0.0002500976,0.00131943,0.0726141,0.0001655117,0.001603577,0.00000761756],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978866,0.0002076379,0.0004277391,0.00005619812,0.000007049115,0.000007522022,0.0009052677,0.00000882405,0.0004931743],"genre_scores_gemma":[0.9962643,0.0001917112,0.0008538346,0.00004870164,0.000006453547,0.00000795194,0.001429018,0.000005191311,0.001192833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001650023,"threshold_uncertainty_score":0.005108476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02292633559166979,"score_gpt":0.341109749860959,"score_spread":0.3181834142692893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}