{"id":"W4211010080","doi":"10.1007/978-1-4939-0694-9_25","title":"HIV-1 Entry Inhibitor Resistance","year":2017,"lang":"en","type":"book-chapter","venue":"","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Maraviroc; Enfuvirtide; CCR5 receptor antagonist; Entry inhibitor; Human immunodeficiency virus (HIV); Medicine; Chemokine receptor; Clinical trial; Pharmacology; Virology; Viral entry; Immunology; Chemokine; Gp41; Virus; Viral replication; Internal medicine; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002783278,0.0007049752,0.0004651169,0.0006549156,0.000429958,0.001814397,0.0006530913,0.0009508654,0.04664351],"category_scores_gemma":[0.0004877381,0.0002129598,0.0002587659,0.0005373425,0.0005363873,0.001516348,0.001088802,0.002288538,0.02766907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008618495,"about_ca_system_score_gemma":0.0008026264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006704936,"about_ca_topic_score_gemma":0.001979289,"domain_scores_codex":[0.9998148,0.00002839873,0.000005667204,0.00002157678,0.0001096358,0.00001991233],"domain_scores_gemma":[0.9999007,0.00004166393,0.000006058277,0.00001084828,0.00002658478,0.00001411762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002101257,0.00004375826,0.00003844255,0.0002878444,0.000004482512,0.0001025674,0.0001117413,0.0003099046,0.001692543,0.06301665,0.4676155,0.4667555],"study_design_scores_gemma":[0.000001980731,0.000006356124,0.00003179017,0.0001101804,0.000001475828,0.000149971,0.00001406828,0.00005672147,0.0003147476,0.007546907,0.9917632,0.000002680205],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.0008759867,0.1387368,0.00952502,0.008482371,0.008987259,0.00007231386,0.0003973409,0.0004270101,0.8324959],"genre_scores_gemma":[0.004163224,0.06829476,0.00310951,0.00472901,0.001690445,0.00006327221,0.000307556,0.0001702267,0.917472],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.04664351,"threshold_uncertainty_score":0.156038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0180059810243448,"score_gpt":0.2520490470047879,"score_spread":0.2340430659804431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}