{"id":"W4211017770","doi":"10.1016/j.atherosclerosis.2022.02.005","title":"The Cholesterol Uptake Capacity: The search for scalable HDL function tests continues","year":2022,"lang":"en","type":"letter","venue":"Atherosclerosis","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Mendelian randomization; Cholesterylester transfer protein; Medicine; Niacin; Internal medicine; Cholesterol; Dyslipidemia; Epidemiology; Lipoprotein; High-density lipoprotein; Reverse cholesterol transport; ABCA1; Endocrinology; Disease; Bioinformatics; Genetics; Biology; Gene; Genetic variants","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01195056,0.001370994,0.003351062,0.001248071,0.00418224,0.006958186,0.002669307,0.06801354,0.009209683],"category_scores_gemma":[0.05109281,0.0009972227,0.002171433,0.001258919,0.008495652,0.01132068,0.004034461,0.07431494,0.00856658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0052229,"about_ca_system_score_gemma":0.007599473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007099911,"about_ca_topic_score_gemma":0.01008881,"domain_scores_codex":[0.9893312,0.003314805,0.001511578,0.001258634,0.003714706,0.0008689958],"domain_scores_gemma":[0.9544449,0.03160597,0.002164017,0.001026927,0.005492448,0.005265659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000875648,0.00005880774,0.0007238679,0.00009513793,0.00001859335,0.0008930962,0.0001669352,0.00006894659,0.0002645779,0.008531759,0.9586914,0.03039929],"study_design_scores_gemma":[0.0001490278,0.0001259926,0.001107002,0.0006897615,0.00003549641,0.001317102,0.0006624767,0.0004563047,0.0001809024,0.0306193,0.9645708,0.00008590801],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0001116921,0.001833044,0.0001942666,0.9902698,0.006558814,0.000006760188,0.00002983617,0.0000203178,0.000975541],"genre_scores_gemma":[0.001442914,0.00258887,0.000585718,0.9449711,0.04797047,0.00003499285,0.00003565067,0.00002994045,0.002340263],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.06801354,"threshold_uncertainty_score":0.06320131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05233833178693929,"score_gpt":0.2651944001334172,"score_spread":0.2128560683464779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}