{"id":"W4211051582","doi":"10.1002/9781119951438.eibc0634","title":"Xanthine Oxidoreductase","year":2011,"lang":"en","type":"other","venue":"Encyclopedia of Inorganic and Bioinorganic Chemistry","topic":"Gout, Hyperuricemia, Uric Acid","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Xanthine dehydrogenase; Hypoxanthine; Chemistry; Oxidoreductase; Xanthine oxidase; Pterin; Biochemistry; Xanthine; Dehydrogenase; NAD+ kinase; Electron acceptor; Stereochemistry; Enzyme; Cofactor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001298579,0.0007268848,0.001152992,0.0001454806,0.00004479375,0.00001031622,0.0003542915,0.001115733,0.03349769],"category_scores_gemma":[0.0001638826,0.0006373987,0.0001820113,0.0004096624,0.000415183,0.00003979869,0.0003045094,0.0007572567,0.0002658733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008393959,"about_ca_system_score_gemma":0.0005307054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000286328,"about_ca_topic_score_gemma":0.000008108936,"domain_scores_codex":[0.9974851,0.00002050338,0.0006731542,0.0008567837,0.0004576958,0.0005067781],"domain_scores_gemma":[0.9977643,0.00003735327,0.0005663089,0.001110215,0.00007858224,0.0004431994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001010823,0.0006765271,0.006069249,0.003925319,0.001228088,0.0002556609,0.0005336766,4.301371e-9,0.2098811,0.00002199214,0.7750166,0.002290686],"study_design_scores_gemma":[0.003717393,0.0002992492,0.001958865,0.00147571,0.003322589,0.002390298,0.0005986908,0.000002131071,0.2298065,0.00008504631,0.7546124,0.001731092],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.03742959,0.01344807,0.00001881706,0.0001880232,0.0004037605,0.0005221132,0.0002218962,0.0004119932,0.9473557],"genre_scores_gemma":[0.04660143,0.01878938,0.002235424,0.0002158092,0.001936393,0.0000153679,0.0003969396,0.001049343,0.9287599],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.03323182,"threshold_uncertainty_score":0.9996077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006224811966036471,"score_gpt":0.2077331965506522,"score_spread":0.2015083845846157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}