{"id":"W4211064310","doi":"10.1002/ajmg.c.30267","title":"Beckwith–Wiedemann syndrome","year":2010,"lang":"en","type":"review","venue":"American Journal of Medical Genetics Part C Seminars in Medical Genetics","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":297,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Beckwith–Wiedemann syndrome; Genomic imprinting; Imprinting (psychology); Epigenetics; Genetics; Biology; Gene; Untranslated region; Gene expression; Messenger RNA; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.004610008,0.001083821,0.003624056,0.0005406445,0.0001010939,0.00007853666,0.003853887,0.00240803,0.0008143939],"category_scores_gemma":[0.003194866,0.0009065783,0.001190459,0.000911309,0.001830609,0.000004965726,0.001231052,0.003670075,0.00006045264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007915745,"about_ca_system_score_gemma":0.003969116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001114116,"about_ca_topic_score_gemma":0.00003714449,"domain_scores_codex":[0.988449,0.0008342937,0.003761414,0.001044862,0.004581993,0.001328464],"domain_scores_gemma":[0.9933464,0.000397282,0.0023146,0.001301186,0.0003162982,0.002324268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001001973,0.0003365779,0.0003197393,0.0008539776,0.000303866,0.0008874785,0.00005313467,0.000007693172,0.00001981311,0.000003595976,0.002662739,0.9945413],"study_design_scores_gemma":[0.0007799935,0.002733636,0.00009972197,0.01260208,0.0005207118,0.01795338,0.0001554859,0.00006148117,0.00003429931,0.00002388031,0.9641468,0.000888517],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02983797,0.9660722,0.0004924682,0.0003642174,0.002513486,0.0004446283,0.0000237456,0.0000110345,0.0002402231],"genre_scores_gemma":[0.001080364,0.990546,0.005355475,0.0006032016,0.001797551,0.00003859724,0.00008235056,0.0002294771,0.0002669979],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9936528,"threshold_uncertainty_score":0.9993385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01786419321986678,"score_gpt":0.3354494338509287,"score_spread":0.317585240631062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}