{"id":"W4211088669","doi":"10.1021/acsnano.1c05901","title":"Scratching the Surface of the Protein Corona: Challenging Measurements and Controversies","year":2022,"lang":"en","type":"review","venue":"ACS Nano","topic":"Polymer Surface Interaction Studies","field":"Materials Science","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal; Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Canada First Research Excellence Fund; Fonds de recherche du Québec – Nature et technologies; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Corona (planetary geology); Protein adsorption; Nanotechnology; Chemistry; Materials science; Biophysics; Chemical physics; Physics; Adsorption; Biology; Physical chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003029087,0.001200331,0.002712597,0.002399903,0.0005565786,0.002259444,0.002143989,0.002610232,0.001461532],"category_scores_gemma":[0.003927141,0.0007641635,0.0008548826,0.00187419,0.002330781,0.003496708,0.001030984,0.002645475,0.00141858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000952651,"about_ca_system_score_gemma":0.001327104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008817961,"about_ca_topic_score_gemma":0.000965727,"domain_scores_codex":[0.9984007,0.0003090912,0.0001605677,0.0003962004,0.0006584468,0.0000749488],"domain_scores_gemma":[0.9956886,0.003281133,0.0002451196,0.0001337734,0.0005905059,0.00006086835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009184121,0.0001045757,0.0006036559,0.06553478,0.0001809141,0.0003548026,0.0004854032,0.001134612,0.01595719,0.01843667,0.00851195,0.8886036],"study_design_scores_gemma":[0.00002145726,0.0005643122,0.00283732,0.01728334,0.0003417078,0.004125452,0.00169949,0.0009489285,0.02269599,0.02021862,0.9290792,0.0001841333],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004586891,0.9974119,0.0009000047,0.0003867339,0.0001891874,0.000006492383,0.0000129082,0.000007906887,0.0006261157],"genre_scores_gemma":[0.003347113,0.9946532,0.0009058052,0.0003067366,0.0003464149,0.00001974962,0.00003485758,0.000006618943,0.0003793445],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003029087,"threshold_uncertainty_score":0.01601958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1085554387614124,"score_gpt":0.3213908637393336,"score_spread":0.2128354249779211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}