{"id":"W4211105381","doi":"10.1016/s0140-6736(07)61090-3","title":"Achondroplasia","year":2007,"lang":"en","type":"review","venue":"The Lancet","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":584,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Achondroplasia; Fibroblast growth factor receptor 3; Fibroblast growth factor receptor; Dwarfism; Mutation; Fibroblast growth factor; Biology; Point mutation; Receptor; Anticipation (artificial intelligence); Genetics; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004130802,0.0002333801,0.0007081919,0.00004260368,0.00006019181,0.0000363017,0.000943731,0.0002992898,0.00005756279],"category_scores_gemma":[0.00009402915,0.000135134,0.0002432881,0.0001390827,0.00009928802,7.694641e-7,0.0002972902,0.0004148723,0.0004310381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001908938,"about_ca_system_score_gemma":0.0001261288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004576804,"about_ca_topic_score_gemma":0.00001061254,"domain_scores_codex":[0.998738,0.0001527072,0.0002042305,0.0002967599,0.0001800918,0.0004282185],"domain_scores_gemma":[0.99872,0.00004675802,0.00008853673,0.00105852,0.00002719699,0.00005897078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000283729,0.00001642468,0.00002891723,0.004495824,0.0001996396,0.00001232585,0.000007369572,2.16231e-7,0.0001904192,0.0001189958,0.1762483,0.8186532],"study_design_scores_gemma":[0.0001015253,0.00004719196,0.00001034712,0.0006365385,0.00004686805,0.00005863366,0.000001178229,1.652493e-7,0.00005986491,0.000009603837,0.9988739,0.0001542221],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000031102,0.9931462,0.00004451472,0.00004834191,0.0001499281,0.0003165875,0.00006828611,0.00001565889,0.006179316],"genre_scores_gemma":[0.00001300707,0.9940396,0.0001024455,0.00009461879,0.002536224,0.0000311865,0.0002591734,0.00005443958,0.00286928],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8226256,"threshold_uncertainty_score":0.5540266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1052761843808152,"score_gpt":0.4031937322636056,"score_spread":0.2979175478827904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}