{"id":"W4211105381","doi":"10.1016/s0140-6736(07)61090-3","title":"Achondroplasia","year":2007,"lang":"en","type":"review","venue":"The Lancet","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":584,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Achondroplasia; Fibroblast growth factor receptor 3; Fibroblast growth factor receptor; Dwarfism; Mutation; Fibroblast growth factor; Biology; Point mutation; Receptor; Anticipation (artificial intelligence); Genetics; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008100723,0.001474179,0.001558678,0.001893296,0.0004784664,0.001089923,0.001125768,0.001848869,0.007923344],"category_scores_gemma":[0.001208188,0.0003328987,0.000404698,0.001605605,0.0008109338,0.001257633,0.0009947546,0.003074079,0.006383604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001043506,"about_ca_system_score_gemma":0.001366172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001514244,"about_ca_topic_score_gemma":0.005088327,"domain_scores_codex":[0.9997202,0.00003868316,0.00002364686,0.00003975807,0.0001446733,0.00003309642],"domain_scores_gemma":[0.9996713,0.0001189293,0.00004141457,0.00001600204,0.00009695505,0.00005522793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001123008,0.00003946306,0.00006770383,0.003832691,0.00004185808,0.0004115468,0.00002180078,0.0001383836,0.001051106,0.003453412,0.2900365,0.7007933],"study_design_scores_gemma":[0.00003527598,0.0000231406,0.0001637292,0.0007686503,0.00003045809,0.0009034674,0.00001705711,0.00002025041,0.0001318019,0.001141116,0.9967586,0.000006409533],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004344312,0.9888633,0.0002296347,0.001712936,0.005168451,0.00000678711,0.00001954319,0.00002424758,0.003931484],"genre_scores_gemma":[0.0007993223,0.9823422,0.0005581137,0.002767506,0.003681591,0.00002379985,0.00005927385,0.000006772202,0.009761415],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007923344,"threshold_uncertainty_score":0.02650619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1052761843808152,"score_gpt":0.4031937322636056,"score_spread":0.2979175478827904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}