{"id":"W4211119516","doi":"10.1016/s2215-0366(21)00429-6","title":"Efficacy and safety of balovaptan for socialisation and communication difficulties in autistic adults in North America and Europe: a phase 3, randomised, placebo-controlled trial","year":2022,"lang":"en","type":"article","venue":"The Lancet Psychiatry","topic":"Autism Spectrum Disorder Research","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"Holland Bloorview Kids Rehabilitation Hospital","funders":"Medical Research Council; F. Hoffmann-La Roche; Roche","keywords":"Phase (matter); MEDLINE; Autism; Socialization","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001421506,0.00200528,0.00402489,0.0005142334,0.0006752724,0.00127003,0.001149901,0.003005519,0.005677938],"category_scores_gemma":[0.002360397,0.0009220567,0.002972712,0.0004584564,0.001829857,0.001353177,0.0004628073,0.003663712,0.001002335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008831431,"about_ca_system_score_gemma":0.001148218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001957352,"about_ca_topic_score_gemma":0.004526287,"domain_scores_codex":[0.9992459,0.000361497,0.00006239967,0.0001499302,0.00005667646,0.0001235695],"domain_scores_gemma":[0.9989218,0.0003472761,0.0002500921,0.00007944313,0.00008122608,0.0003203299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9779378,0.004047038,0.0006119994,0.001025444,0.001712572,0.00006421085,0.00008756141,0.0001666432,0.002265029,0.00006247636,0.0005821541,0.01143709],"study_design_scores_gemma":[0.9577037,0.03858462,0.002047797,0.00007564204,0.0007274878,0.00003933437,0.00005380064,0.0001464852,0.0001952609,0.00009650915,0.0003097983,0.00001962861],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849253,0.009437583,0.0003775507,0.0007200773,0.0006159961,0.001687429,0.0006176652,0.0001123786,0.001506055],"genre_scores_gemma":[0.9884691,0.004894727,0.0008008858,0.001016371,0.0003691509,0.002265005,0.0005259147,0.00002873927,0.001630181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005677938,"threshold_uncertainty_score":0.01899457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02648593691385528,"score_gpt":0.3134449434929707,"score_spread":0.2869590065791154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}