{"id":"W4211122789","doi":"10.1007/s43441-022-00378-0","title":"Ivermectin in COVID-19: The Case for a Moratorium on Prescriptions","year":2022,"lang":"en","type":"article","venue":"Therapeutic Innovation & Regulatory Science","topic":"Parasitic Diseases Research and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Duke Clinical Research Institute; Canadian Institutes of Health Research; Genentech; U.S. Food and Drug Administration; National Institutes of Health; Astellas Pharma; Brigham and Women's Hospital; British Heart Foundation; Regeneron Pharmaceuticals; Sanofi; AstraZeneca; McMaster University; Amgen; Pfizer; GlaxoSmithKline","keywords":"Ivermectin; Medicine; Medical prescription; Pharmacy; Randomized controlled trial; Clinical trial; Intensive care medicine; Onchocerciasis; Health care; Drug; Pharmacology; Family medicine; Surgery; Internal medicine; Veterinary medicine; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02669881,0.000415129,0.001160257,0.0008364138,0.005069857,0.009139264,0.003087722,0.02099848,0.02097657],"category_scores_gemma":[0.07287949,0.0005502347,0.001552135,0.0007564613,0.01084614,0.009138064,0.006075838,0.02294713,0.002781621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006527421,"about_ca_system_score_gemma":0.01459224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007999111,"about_ca_topic_score_gemma":0.01703008,"domain_scores_codex":[0.9737415,0.009001432,0.001460148,0.002647997,0.008062698,0.005086093],"domain_scores_gemma":[0.9432059,0.03297,0.003680243,0.004725242,0.007750391,0.007668241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005359228,0.0002662358,0.00692161,0.0003857369,0.000161621,0.00251789,0.002293082,0.0005947399,0.003106519,0.311774,0.489029,0.1824137],"study_design_scores_gemma":[0.0001282778,0.0002396328,0.006203296,0.001838707,0.00009080156,0.001121429,0.001599287,0.0008807249,0.001650504,0.06514452,0.9209753,0.0001275306],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.007576222,0.003236033,0.001805859,0.949802,0.004184037,0.00002638687,0.00007316592,0.00006768677,0.03322845],"genre_scores_gemma":[0.207981,0.005127789,0.004370544,0.7455506,0.01247746,0.00009891484,0.00009679853,0.0002506076,0.02404615],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02669881,"threshold_uncertainty_score":0.1411985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08322595122785655,"score_gpt":0.3996786187321096,"score_spread":0.316452667504253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}