{"id":"W4211194455","doi":"10.1002/9781405165518.a0024149.pub2","title":"Regulation and Function of the <i> <scp>MYC</scp> </i> Oncogene","year":2019,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Biology; SUMO protein; Oncogene; Transcription factor; N-Myc; Epigenetics; Enhancer; Gene; Cancer research; Cancer; Cell biology; Genetics; Ubiquitin; Cell cycle; Cell culture; Neuroblastoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001026089,0.0002888443,0.0001294341,0.0003909572,0.0002967663,0.0009529174,0.0003243904,0.0003382233,0.003479629],"category_scores_gemma":[0.0001739187,0.0001441078,0.000297131,0.0002802821,0.0003592152,0.0003408584,0.0004003537,0.0007711246,0.001751162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008829979,"about_ca_system_score_gemma":0.0002639712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001435108,"about_ca_topic_score_gemma":0.0009845613,"domain_scores_codex":[0.9998223,0.00001552449,0.000009772384,0.00004740894,0.00006376164,0.00004119463],"domain_scores_gemma":[0.9998193,0.00002702648,0.00004966855,0.00002044859,0.00003421681,0.00004925586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009917359,0.00002115761,0.0004751529,0.00004595895,0.000006302147,0.0001080209,0.00001438325,0.0001321358,0.9918383,0.001783589,0.0006416758,0.004834234],"study_design_scores_gemma":[0.00002262439,0.0001691902,0.03599937,0.00003967743,0.0000230707,0.001547312,0.00009787498,0.003821051,0.9227552,0.000908133,0.0345955,0.00002082166],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9389263,0.01698923,0.009864582,0.0009032143,0.0001765238,0.00005748316,0.00360342,0.0004913631,0.02898792],"genre_scores_gemma":[0.9833303,0.002090711,0.001347917,0.0001814422,0.00002237951,0.00003015639,0.002547538,0.00009596778,0.01035365],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.003479629,"threshold_uncertainty_score":0.01164055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01075606512898357,"score_gpt":0.2269896859657785,"score_spread":0.2162336208367949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}