{"id":"W4211205853","doi":"10.1002/anbr.202100159","title":"Revealing Layer‐Specific Ultrastructure and Nanomechanics of Fibrillar Collagen in Human Aorta via Atomic Force Microscopy Testing: Implications on Tissue Mechanics at Macroscopic Scale","year":2022,"lang":"en","type":"article","venue":"Advanced NanoBiomed Research","topic":"Elasticity and Material Modeling","field":"Engineering","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of New Brunswick; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Deutsches Krebsforschungszentrum; Fonds de Recherche du Québec-Société et Culture; McGill University","keywords":"Nanomechanics; Nanoindentation; Indentation; Extracellular matrix; Adventitia; Stiffness; Materials science; Ultrastructure; Aorta; Elasticity (physics); Biomedical engineering; Atomic force microscopy; Biophysics; Anatomy; Composite material; Chemistry; Nanotechnology; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001620976,0.000153143,0.00005827636,0.0002281077,0.000158079,0.000150333,0.000126495,0.0003466134,0.0006278588],"category_scores_gemma":[0.0002735351,0.0001251715,0.00007719512,0.0001365752,0.0001831085,0.0001502791,0.0001204933,0.000167083,0.00009822239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008759049,"about_ca_system_score_gemma":0.0001141285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001018446,"about_ca_topic_score_gemma":0.002242979,"domain_scores_codex":[0.9999392,0.000008390891,0.000004531262,0.00001840295,0.00001988642,0.000009593223],"domain_scores_gemma":[0.9998432,0.00006380963,0.00003297051,0.00002078302,0.00002336321,0.00001573744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001862804,0.000009505365,0.00123105,0.00001649525,0.000001548273,0.00005041922,0.0000516136,0.0001089699,0.9967474,0.00003029927,0.00001472274,0.001719313],"study_design_scores_gemma":[0.000007468804,0.0001926669,0.1192167,0.00001249149,0.000022224,0.0008541975,0.0002800398,0.01174653,0.8665012,0.0001914388,0.0009519992,0.00002319176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918031,0.0003745914,0.007049442,0.00004502117,0.000009842812,0.000009669978,0.0001262046,0.00003802286,0.0005442349],"genre_scores_gemma":[0.9915081,0.0003382871,0.007519781,0.00002300121,0.000005532893,0.00001286117,0.00006355643,0.000006936329,0.0005220153],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001018446,"threshold_uncertainty_score":0.002100348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03564984734723001,"score_gpt":0.3241298160570786,"score_spread":0.2884799687098485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}