{"id":"W4211245805","doi":"10.3410/f.718002437.793478670","title":"Faculty Opinions recommendation of Upregulation of the hyperpolarization-activated current increases pacemaker activity of the sinoatrial node and heart rate during pregnancy in mice.","year":2013,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Cardiovascular Issues in Pregnancy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"","keywords":"Sinoatrial node; Downregulation and upregulation; Hyperpolarization (physics); Pacemaker potential; Heart rate; Internal medicine; Cardiology; Medicine; Pregnancy; Chemistry; Electrophysiology; Biology; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001123189,0.00143142,0.001027655,0.001954872,0.0004745391,0.001549395,0.001637101,0.001842115,0.02509168],"category_scores_gemma":[0.007064829,0.0004016093,0.001830075,0.002345373,0.0002467866,0.000737093,0.001109308,0.001170286,0.02163444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001081337,"about_ca_system_score_gemma":0.002061019,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0208424,"about_ca_topic_score_gemma":0.06518998,"domain_scores_codex":[0.9992285,0.0001370582,0.000110234,0.0002141853,0.0002203723,0.00008977274],"domain_scores_gemma":[0.9970696,0.001020969,0.0005030633,0.0003780256,0.0006778035,0.0003505595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003570031,0.0000539207,0.006179353,0.001992799,0.0002100645,0.00005139087,0.00002301665,0.00035984,0.0005165951,0.0002737374,0.982213,0.007769239],"study_design_scores_gemma":[0.001328812,0.0001236256,0.0544929,0.001128376,0.0005743874,0.0003093009,0.00008738822,0.001888218,0.001927313,0.001276253,0.9367614,0.0001018133],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0006753421,0.0003022687,0.0001055577,0.0002173805,0.00006384803,0.00002098254,0.9974707,0.000354991,0.0007889378],"genre_scores_gemma":[0.001947272,0.0002934489,0.0005950248,0.0002038053,0.00002944911,0.0001106362,0.995434,0.00006511711,0.00132131],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.02509168,"threshold_uncertainty_score":0.08394003,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02922048736979029,"score_gpt":0.335102073774692,"score_spread":0.3058815864049018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}