{"id":"W4212767672","doi":"10.1183/13993003.01500-2021","title":"<i>Pseudomonas aeruginosa</i>membrane vesicles cause endothelial barrier failure and lung injury","year":2022,"lang":"en","type":"letter","venue":"European Respiratory Journal","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University; Hospital for Sick Children; University of Toronto; University of Guelph; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Bundesministerium für Bildung und Forschung; Canadian Hematology Society; Deutsche Forschungsgemeinschaft; Canadian Lung Association; International Anesthesia Research Society","keywords":"Pseudomonas aeruginosa; Vesicle; Microbiology; Inflammasome; Lung; Chemistry; Membrane; Cell biology; Biology; Bacteria; Immunology; Medicine; Inflammation; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007737166,0.0006858495,0.0006056426,0.0003683288,0.001551891,0.001469044,0.0004869924,0.01527215,0.007150726],"category_scores_gemma":[0.004924664,0.0003147289,0.0007394807,0.0002703031,0.001142651,0.00115708,0.0004647977,0.01029368,0.00796131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002047697,"about_ca_system_score_gemma":0.0007386601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00173924,"about_ca_topic_score_gemma":0.001584071,"domain_scores_codex":[0.9994177,0.0001723393,0.00005913937,0.000068091,0.0001887501,0.00009409731],"domain_scores_gemma":[0.9985595,0.000639124,0.0001221298,0.0000781785,0.0003358245,0.0002652527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002012511,0.0001034014,0.001625849,0.0000984958,0.00002668839,0.02178811,0.0001001121,0.00009974099,0.002035145,0.002548832,0.9557847,0.01558756],"study_design_scores_gemma":[0.0004353331,0.0004330383,0.005671526,0.0003272792,0.00007067309,0.04540823,0.0005553308,0.001465565,0.002512137,0.01247992,0.9305588,0.00008229611],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.004567847,0.002810094,0.0003385238,0.947147,0.02870679,0.00004137888,0.0001116361,0.0001538254,0.0161229],"genre_scores_gemma":[0.05502306,0.006461852,0.0007208035,0.7951508,0.1101443,0.0000929776,0.0001599527,0.00008585428,0.03216033],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01527215,"threshold_uncertainty_score":0.02392161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01530679513942905,"score_gpt":0.2353383530802182,"score_spread":0.2200315579407891,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}