{"id":"W4212772680","doi":"10.3390/cancers14040957","title":"Risk of Second Primary Thyroid Cancer in Women with Breast Cancer","year":2022,"lang":"en","type":"article","venue":"Cancers","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital","funders":"Breast Cancer Campaign","keywords":"CHEK2; Breast cancer; Medicine; Thyroid cancer; Oncology; Internal medicine; Cancer; Population; Gynecology; Thyroid; Mutation; Germline mutation; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000340775,0.0002366991,0.0003183979,0.0005762324,0.0002148263,0.00041293,0.0002349702,0.000454804,0.001507109],"category_scores_gemma":[0.001711174,0.0003143385,0.0004550937,0.0006052387,0.0001327802,0.0002617619,0.0003206625,0.0004742501,0.000358055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000263295,"about_ca_system_score_gemma":0.0002483757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006327351,"about_ca_topic_score_gemma":0.005230955,"domain_scores_codex":[0.9997817,0.00004429452,0.00001397634,0.00006564986,0.00004183558,0.00005265705],"domain_scores_gemma":[0.999465,0.0001031941,0.0002474728,0.00004760662,0.00004808729,0.0000885938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001312757,0.00001100845,0.9975489,0.000006939373,0.00003600564,0.000127082,0.00003724866,0.00004252268,0.0001854643,0.00001265508,0.00006693049,0.001794072],"study_design_scores_gemma":[0.0000104953,0.00009756094,0.9978487,0.000005416241,0.00004487921,0.001112819,0.00008211711,0.0003296223,0.0001129461,0.00004720066,0.0003038894,0.000004270904],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978552,0.0008514241,0.0002173907,0.00006844123,0.000008569521,0.000007267505,0.0002706358,0.00000806805,0.0007128917],"genre_scores_gemma":[0.9988323,0.0003632233,0.0001161017,0.00002046869,0.0000117966,0.000005722323,0.0002400836,0.00000270258,0.0004076939],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006327351,"threshold_uncertainty_score":0.01258105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004335294492123098,"score_gpt":0.2310220821183654,"score_spread":0.2266867876262423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}