{"id":"W4212798424","doi":"10.1016/j.jcmgh.2022.02.011","title":"Glucagon-Like Peptide-2 Stimulates S-Phase Entry of Intestinal Lgr5+ Stem Cells","year":2022,"lang":"en","type":"article","venue":"Cellular and Molecular Gastroenterology and Hepatology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Muscular Dystrophy Canada","funders":"Banting and Best Diabetes Centre, University of Toronto; Canadian Institutes of Health Research; Novo Nordisk; Novo Nordisk Fonden; University of Toronto; Lunds Universitet; Canadian Association of Gastroenterology","keywords":"LGR5; Stem cell; Biology; Cell cycle; Glucagon-like peptide-2; Internal medicine; Endocrinology; Intestinal epithelium; Cell biology; Molecular biology; Cell; Cancer stem cell; Epithelium; Biochemistry; Medicine; Peptide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008244911,0.0002366229,0.0001433715,0.0001640133,0.000058445,0.0001749205,0.00007798272,0.0001452873,0.001740283],"category_scores_gemma":[0.00005687168,0.00006644738,0.0001575813,0.00007847395,0.0001698891,0.0001333469,0.0001430917,0.0003078123,0.0002188098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001923157,"about_ca_system_score_gemma":0.0001277215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002635663,"about_ca_topic_score_gemma":0.000641197,"domain_scores_codex":[0.9999475,0.000008932183,0.000004848884,0.00001131104,0.00001370302,0.00001366686],"domain_scores_gemma":[0.9999462,0.000007363972,0.00001514802,0.000004347417,0.000004273943,0.00002265922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002173172,0.00002193142,0.0004116822,0.00005192505,0.000003344953,0.00004176025,0.000008981051,0.0000262528,0.9973887,0.00003844974,0.00006183147,0.001727856],"study_design_scores_gemma":[0.00006769505,0.001161924,0.02527622,0.00001933442,0.000019996,0.0002190957,0.00007770681,0.000558527,0.9693467,0.00004421057,0.003205183,0.000003408691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961753,0.001226145,0.0008842392,0.00008952047,0.00002760728,0.00001320407,0.0002000824,0.00006366972,0.001320242],"genre_scores_gemma":[0.9961573,0.0006194719,0.0009305244,0.0001009199,0.00001578684,0.00002610917,0.0002931232,0.00001127098,0.001845453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001740283,"threshold_uncertainty_score":0.005821824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00898717945186504,"score_gpt":0.2326760549056534,"score_spread":0.2236888754537884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}