{"id":"W4212827490","doi":"10.1093/jcag/gwab049.042","title":"A43 HIGH MUC2 MUCIN BIOSYNTHESIS BY GOBLET CELLS UNDER METABOLIC STRESS PRODUCE ELEVATED LEVELS OF PRO-INFLAMMATORY CYTOKINES","year":2022,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Mucin; Goblet cell; Mucus; Cell biology; Biology; Innate immune system; Mucin 2; Chemokine; Proinflammatory cytokine; Secretion; Microbiology; Immunology; Immune system; Inflammation; Gene expression; Biochemistry; Epithelium","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001635654,0.0003682802,0.0005384312,0.0002639116,0.0002101608,0.0004942851,0.0001106633,0.0005032015,0.003295719],"category_scores_gemma":[0.0001420357,0.0001758518,0.0005102018,0.0001984662,0.0003384121,0.0003493012,0.0002731385,0.001105088,0.0006788973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002212697,"about_ca_system_score_gemma":0.0001772564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006344444,"about_ca_topic_score_gemma":0.0006548804,"domain_scores_codex":[0.9996508,0.0000427532,0.00003685637,0.00009048583,0.0001009492,0.00007817055],"domain_scores_gemma":[0.9998205,0.00001892805,0.0000480628,0.00002724227,0.00002360189,0.00006171145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008125331,0.00001404592,0.0001684438,0.00003793466,0.000004220815,0.00004517087,0.00001122015,0.00001538486,0.9993291,0.00002561032,0.00003958056,0.0002281632],"study_design_scores_gemma":[0.00002825476,0.0006479917,0.01927536,0.00002012146,0.0000313523,0.0005964663,0.0002229595,0.00085116,0.9745928,0.0001306383,0.003584297,0.00001852222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917839,0.001517267,0.003450567,0.0002895973,0.0001126496,0.00004458895,0.001292961,0.0001702612,0.001338198],"genre_scores_gemma":[0.9903155,0.0007970246,0.002417933,0.0002445501,0.00002327878,0.0001323347,0.001527405,0.00004660267,0.004495346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003295719,"threshold_uncertainty_score":0.01102531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007984499506250815,"score_gpt":0.2175393631018081,"score_spread":0.2095548635955573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}