{"id":"W4212837931","doi":"10.1093/jcag/gwab049.036","title":"A37 EFFICACY AND SAFETY OF RISANKIZUMAB AS MAINTENANCE THERAPY IN PATIENTS WITH CROHN’S DISEASE: 52 WEEK RESULTS FROM THE PHASE 3 FORTIFY STUDY","year":2022,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Placebo; Gastroenterology; Internal medicine; Abdominal pain; Crohn's disease; Clinical endpoint; Phases of clinical research; Calprotectin; Maintenance therapy; Clinical trial; Randomized controlled trial; Inflammatory bowel disease; Disease; Chemotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003275394,0.0009940648,0.002221123,0.0002952005,0.0003907688,0.0009970664,0.0005989284,0.001332469,0.003276832],"category_scores_gemma":[0.001228476,0.0004664228,0.002142618,0.0002412855,0.0006300188,0.0008062719,0.0003788092,0.002259868,0.0009833529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00048099,"about_ca_system_score_gemma":0.0006953885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005452839,"about_ca_topic_score_gemma":0.001033011,"domain_scores_codex":[0.9989508,0.0005834398,0.00006245076,0.0001271866,0.0001366996,0.0001393565],"domain_scores_gemma":[0.9987699,0.0002303525,0.0003465347,0.0001701531,0.0001071,0.000375771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8310311,0.02611818,0.008640267,0.0007347323,0.001955221,0.0001935582,0.0002428483,0.0009934161,0.04653225,0.00009595101,0.002952843,0.0805096],"study_design_scores_gemma":[0.4989569,0.4480555,0.04255958,0.00005259862,0.001041702,0.0002644433,0.00006080437,0.0008209766,0.004972797,0.00012607,0.003031366,0.00005729009],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931895,0.003126669,0.0004246307,0.0003056818,0.00005923787,0.0008178456,0.001063581,0.00008586414,0.0009270759],"genre_scores_gemma":[0.9925063,0.00113657,0.000958529,0.000702763,0.0001493844,0.0009293705,0.002024238,0.00002984099,0.001562963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003276832,"threshold_uncertainty_score":0.01732212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005181777092609133,"score_gpt":0.2175361867197366,"score_spread":0.2123544096271275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}