{"id":"W4212851543","doi":"10.1002/cncr.34106","title":"Ofatumumab plus HyperCVAD/HD‐MA induction leads to high rates of minimal residual disease negativity in patients with newly diagnosed mantle cell lymphoma: Results of a phase 2 study","year":2022,"lang":"en","type":"article","venue":"Cancer","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Cancer Institute; National Comprehensive Cancer Network; Roswell Park Cancer Institute","keywords":"Medicine; Internal medicine; Mantle cell lymphoma; Minimal residual disease; Ofatumumab; Rituximab; Surgery; Oncology; Gastroenterology; Lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00199995,0.0006602612,0.001370003,0.0002272337,0.0002612894,0.0006287717,0.0005106623,0.000591729,0.0008575227],"category_scores_gemma":[0.001001333,0.0003430437,0.001002448,0.0002309577,0.0003823778,0.0004275181,0.0001833354,0.001496379,0.0002789691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006742589,"about_ca_system_score_gemma":0.0005355569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004670546,"about_ca_topic_score_gemma":0.0009282235,"domain_scores_codex":[0.9994463,0.0002813764,0.00004128598,0.00008622192,0.00007755434,0.00006719909],"domain_scores_gemma":[0.9990562,0.0003356222,0.0002206211,0.0001046002,0.00004928951,0.0002336966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4222755,0.07246441,0.08497841,0.0007668075,0.003362848,0.0016231,0.0008810377,0.002847338,0.1382392,0.0001550754,0.002241089,0.2701652],"study_design_scores_gemma":[0.1603359,0.6839517,0.1308511,0.0000465432,0.001527885,0.002730729,0.00008928582,0.002446234,0.01445648,0.0000886253,0.003426787,0.0000488187],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982658,0.001031252,0.0001676269,0.0000551262,0.00001595491,0.0001481976,0.0000747769,0.00001606839,0.0002252683],"genre_scores_gemma":[0.9982753,0.0004728487,0.0003834722,0.0001446649,0.00004783413,0.0001270392,0.0003035089,0.0000074204,0.000237933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00199995,"threshold_uncertainty_score":0.01057684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01960594937588766,"score_gpt":0.2912329741779556,"score_spread":0.2716270248020679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}