{"id":"W4212862659","doi":"10.3390/molecules27041338","title":"Synthesis of (+)-(R)-Tiruchanduramine","year":2022,"lang":"en","type":"article","venue":"Molecules","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island","funders":"European Regional Development Fund; Bangor University; Natural Sciences and Engineering Research Council of Canada; Atlantic Canada Opportunities Agency; Engineering and Physical Sciences Research Council; Canada Foundation for Innovation","keywords":"Total synthesis; Stereochemistry; Yield (engineering); Chemistry; Alkaloid; Convergent synthesis; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002602785,0.0004500352,0.0004821801,0.000311445,0.0002919966,0.00029241,0.0006769054,0.0003667584,0.004405608],"category_scores_gemma":[0.000217931,0.0001728314,0.0003559086,0.0003067384,0.0001406439,0.0002998498,0.0003974691,0.000513942,0.002336836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003401338,"about_ca_system_score_gemma":0.0006283823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008465536,"about_ca_topic_score_gemma":0.001373536,"domain_scores_codex":[0.9998498,0.00002503945,0.00001579938,0.00003317827,0.00003216699,0.0000438734],"domain_scores_gemma":[0.9999145,0.000006878884,0.00001360261,0.00001472007,0.00002517994,0.00002507022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002153695,0.00005360062,0.0001181889,0.0003264381,0.00002698266,0.0004986335,0.00009970574,0.0004149637,0.981742,0.001664748,0.0004405372,0.01439885],"study_design_scores_gemma":[0.0001632293,0.002057412,0.001492146,0.00004642106,0.00007862043,0.002010674,0.00007933271,0.0009780404,0.9535501,0.0004812238,0.0389837,0.00007897317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8631195,0.006147605,0.07098758,0.0004662169,0.0003605218,0.001143305,0.005586955,0.001153133,0.05103532],"genre_scores_gemma":[0.950209,0.003351181,0.03179606,0.0001068175,0.00004148472,0.0002443304,0.002183525,0.000109854,0.01195778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004405608,"threshold_uncertainty_score":0.01473826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005822145028275053,"score_gpt":0.214895278605097,"score_spread":0.209073133576822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}