{"id":"W4212864413","doi":"10.1200/jco.2022.40.6_suppl.tps210","title":"PSMAddition: A phase 3 trial to compare treatment with <sup>177</sup>Lu-PSMA-617 plus standard of care (SOC) versus SOC alone in patients with metastatic hormone-sensitive prostate cancer.","year":2022,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Medicine; Prostate cancer; Clinical endpoint; Androgen deprivation therapy; Oncology; Internal medicine; Hazard ratio; Urology; Nuclear medicine; Randomized controlled trial; Cancer; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008739025,0.0002696354,0.002522263,0.0002840442,0.0001277655,0.00001136844,0.0001374962,0.00007001959,0.0001942988],"category_scores_gemma":[0.0002366356,0.0001642773,0.0002932634,0.0004574483,0.0003008988,0.0001110802,0.00007673609,0.0008006342,0.000002188793],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003181254,"about_ca_system_score_gemma":0.006593315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002017952,"about_ca_topic_score_gemma":0.0005981609,"domain_scores_codex":[0.995712,0.0007265504,0.001626463,0.0003479439,0.001160632,0.0004263926],"domain_scores_gemma":[0.9959282,0.001041787,0.00118823,0.0002257521,0.001115684,0.0005003291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9267083,0.005543941,0.008570897,0.00005240503,0.001878655,0.002350804,0.004756921,0.001683074,0.000005092818,0.000004447415,0.00146062,0.04698485],"study_design_scores_gemma":[0.5565583,0.4180963,0.007715148,0.0001578851,0.001125444,0.0000337338,0.008862293,0.00006657198,0.00009711528,0.000008068461,0.007127116,0.0001521116],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922819,0.0008411007,0.00001373321,0.002851703,0.0003267105,0.0023753,0.001085585,0.000008596794,0.0002154234],"genre_scores_gemma":[0.9973208,0.0005241574,0.001043553,0.0002125685,0.0002991955,0.0002292586,0.0002183186,0.00003344236,0.0001187271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4125523,"threshold_uncertainty_score":0.9990384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1200603837742536,"score_gpt":0.4761127552550605,"score_spread":0.3560523714808068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}