{"id":"W4212865470","doi":"10.3390/cancers14040962","title":"Modeling the Role of Cancer-Associated Fibroblasts in Tumor Cell Invasion","year":2022,"lang":"en","type":"review","venue":"Cancers","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Princess Margaret Cancer Foundation","keywords":"Extracellular matrix; Stromal cell; Metastasis; Tumor microenvironment; Cancer cell; Biology; Cancer-Associated Fibroblasts; Stroma; Tumor progression; Cancer research; Cell; Cancer; Tumor cells; Cell biology; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003165944,0.0002986231,0.001502393,0.0001898083,0.00006391235,0.000007460622,0.0002517628,0.0001051388,0.000741106],"category_scores_gemma":[0.00004936187,0.0002106572,0.0004839465,0.000763381,0.0000456536,0.00002681899,0.000119727,0.0006521475,0.000003358474],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004730257,"about_ca_system_score_gemma":0.004668114,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01752166,"about_ca_topic_score_gemma":0.002966322,"domain_scores_codex":[0.9981667,0.0001283695,0.000626146,0.0003796999,0.0003696426,0.0003294568],"domain_scores_gemma":[0.9989713,0.0001048801,0.0003866494,0.0004039641,0.00004218565,0.00009096917],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004862982,0.00003770967,0.0000207376,0.01029083,0.0001664244,0.00001965024,0.0002901186,0.007355291,0.00003156895,0.000005938099,0.0004909346,0.9812422],"study_design_scores_gemma":[0.0005111987,0.00008671646,7.548434e-7,0.01012259,0.001001388,0.000004985929,0.0003433396,0.001643084,0.00008368897,0.00001060667,0.9859946,0.0001970546],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009993778,0.9953614,0.000001398658,0.00001386825,0.0003442713,0.0009215435,0.0001897605,0.00001772646,0.002150594],"genre_scores_gemma":[0.002126605,0.9966842,0.00001829521,0.00009182875,0.0001147113,0.0004673972,0.00009465336,0.00006925555,0.0003330433],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9855037,"threshold_uncertainty_score":0.9990904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.051861681663282,"score_gpt":0.3188143125890022,"score_spread":0.2669526309257202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}