{"id":"W4212871088","doi":"10.1111/apt.16788","title":"Review article: switching patients with chronic hepatitis B to tenofovir alafenamide—a review of current data","year":2022,"lang":"en","type":"review","venue":"Alimentary Pharmacology & Therapeutics","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Gilead Sciences","keywords":"Tenofovir alafenamide; Medicine; Entecavir; Tenofovir; Renal function; Hepatitis B; Internal medicine; Hepatitis B virus; Creatinine; Chronic hepatitis; Gastroenterology; Urology; Immunology; Human immunodeficiency virus (HIV); Viral load; Virus; Lamivudine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009080929,0.0008625191,0.003877054,0.0002194553,0.0002102384,0.000007774775,0.001120071,0.0001023348,0.003467365],"category_scores_gemma":[0.000007095647,0.0006582231,0.0003721041,0.0009586553,0.0001433099,0.0001588123,0.001497847,0.001156926,0.0001394804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00106119,"about_ca_system_score_gemma":0.001295271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002530906,"about_ca_topic_score_gemma":0.0001442136,"domain_scores_codex":[0.9946086,0.0009329839,0.001822868,0.001075774,0.0008304632,0.000729351],"domain_scores_gemma":[0.9964128,0.0004089512,0.001042492,0.001665283,0.0001988905,0.0002715733],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000309211,0.0006387057,0.001959952,0.2696536,0.0121177,0.00003414786,0.00003025512,1.102466e-7,0.000003755251,0.000001629513,0.01975241,0.6957768],"study_design_scores_gemma":[0.0006892486,0.0007920821,0.0001046952,0.196137,0.08870223,0.00003255941,8.34779e-7,0.000003025616,0.000004509983,9.045935e-7,0.7131289,0.0004040146],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003976165,0.9881088,0.00001125351,0.001521519,0.001116807,0.007835142,0.001241298,0.00007124384,0.00005420647],"genre_scores_gemma":[0.000006312227,0.9389892,0.0002258373,0.05569752,0.0002722026,0.0008757136,0.003748094,0.0001624461,0.00002272658],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6953728,"threshold_uncertainty_score":0.9995869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1396497451120938,"score_gpt":0.4368814625318294,"score_spread":0.2972317174197355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}