{"id":"W4212929726","doi":"10.1039/d1ra08443g","title":"Solvent-free synthesis of 3,5-isoxazoles <i>via</i> 1,3-dipolar cycloaddition of terminal alkynes and hydroxyimidoyl chlorides over Cu/Al<sub>2</sub>O<sub>3</sub> surface under ball-milling conditions","year":2022,"lang":"en","type":"article","venue":"RSC Advances","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Centre in Green Chemistry and Catalysis; Concordia University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Centre in Green Chemistry and Catalysis","keywords":"Terminal (telecommunication); Cycloaddition; Solvent; Chemistry; 1,3-Dipolar cycloaddition; Dipole; Combinatorial chemistry; Computational chemistry; Organic chemistry; Catalysis; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001242812,0.0005027642,0.0003188891,0.0001541877,0.0001422865,0.0003076914,0.0004661834,0.0003272141,0.001936076],"category_scores_gemma":[0.0001197587,0.0002293236,0.0002637649,0.0001869333,0.0001781298,0.000371016,0.0002109832,0.0005417187,0.00105591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002876477,"about_ca_system_score_gemma":0.0002374446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002855525,"about_ca_topic_score_gemma":0.0008516561,"domain_scores_codex":[0.9998872,0.00001158602,0.0000120559,0.00002908311,0.00002972213,0.00003036389],"domain_scores_gemma":[0.9999272,0.000006369797,0.00003078176,0.00001134062,0.00001163596,0.00001273436],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000306355,0.00001836237,0.00002690722,0.00009862323,0.000005870846,0.00005782101,0.00001454476,0.0001027479,0.9955367,0.0003674498,0.0001972082,0.003543227],"study_design_scores_gemma":[0.000009995384,0.0001164296,0.0002452286,0.000002645986,0.000006177606,0.00007404907,0.000005867707,0.0001685057,0.9953917,0.00003942927,0.003934089,0.00000600259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8631558,0.00624375,0.1001501,0.0004381476,0.0004493879,0.000462346,0.002246797,0.001725611,0.02512811],"genre_scores_gemma":[0.9681314,0.002524691,0.02229613,0.00009239858,0.00003424484,0.0001186148,0.0006276773,0.0001023352,0.006072426],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001936076,"threshold_uncertainty_score":0.00647682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008274566305308973,"score_gpt":0.2351052724416116,"score_spread":0.2268307061363026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}