{"id":"W4212932139","doi":"10.3390/nu14040786","title":"Cancer Cell Inhibiting Sea Cucumber (Holothuria leucospilota) Protein as a Novel Anti-Cancer Drug","year":2022,"lang":"en","type":"article","venue":"Nutrients","topic":"Echinoderm biology and ecology","field":"Agricultural and Biological Sciences","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"HaCaT; Cancer; Cancer cell; Biology; Cell culture; Pharmacology; Chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002527404,0.0001789265,0.0002210311,0.00001141931,0.0008010036,0.00002485395,0.0003428991,0.0001029043,0.0083497],"category_scores_gemma":[0.00001928087,0.0000864677,0.00007935294,0.0002887589,0.0000733186,0.0001225697,0.0003533213,0.0003359596,0.00009150508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001222425,"about_ca_system_score_gemma":0.00002551232,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0110195,"about_ca_topic_score_gemma":0.007733033,"domain_scores_codex":[0.9984421,0.0001195442,0.0002375921,0.0004831835,0.0002068694,0.0005106907],"domain_scores_gemma":[0.9995622,0.00005976633,0.0001697509,0.00006333067,0.00004714117,0.00009779901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008821465,0.0005594625,0.3872615,0.00001151934,0.00002020014,0.000008318118,0.0001635961,0.00002288727,0.6064664,0.0001888773,0.002929457,0.002279629],"study_design_scores_gemma":[0.003892851,0.001259597,0.2282833,0.00007827387,0.0000723059,0.00003853066,0.001889895,0.0005430278,0.4895262,0.00162942,0.271203,0.001583597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934976,0.0005325424,4.065555e-7,0.001630666,0.0004444827,0.0004691749,0.0002646259,0.0000914576,0.003069115],"genre_scores_gemma":[0.9925296,0.00007849868,0.00002293139,0.001495925,0.0002590722,0.0005654191,0.00008879398,0.000002832149,0.004956928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2682736,"threshold_uncertainty_score":0.9955662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01718991932034075,"score_gpt":0.2361293041167807,"score_spread":0.21893938479644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}