{"id":"W4212937333","doi":"10.1093/jcag/gwab049.019","title":"A20 INTESTINAL SMOOTH MUSCLE AND FIBROSTENOSIS: TARGETING NR4A1 TO MODULATE PROLIFERATIVE SIGNALLING","year":2022,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Platelet-derived growth factor receptor; Cancer research; Cell growth; Biology; Receptor; Hedgehog signaling pathway; Signal transduction; Muscle hypertrophy; Inflammation; Fibrosis; Platelet-derived growth factor; Growth factor; Medicine; Cell biology; Immunology; Internal medicine; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000342989,0.0003938725,0.000441598,0.0002862858,0.0001960841,0.0003691495,0.0003994099,0.0005069224,0.003244017],"category_scores_gemma":[0.000127944,0.0001954004,0.0004089803,0.0001698816,0.0002935944,0.0002611276,0.0002159698,0.001044614,0.0009041792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002810908,"about_ca_system_score_gemma":0.0002642368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003910545,"about_ca_topic_score_gemma":0.00103011,"domain_scores_codex":[0.9997717,0.00004059392,0.00002260513,0.00004566039,0.00005608279,0.00006326465],"domain_scores_gemma":[0.9998901,0.0000130818,0.00002972482,0.00001093011,0.00001298391,0.00004323588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005492439,0.0001201603,0.0001299269,0.0002212778,0.00001382792,0.00005074287,0.00001805136,0.0001086657,0.9952081,0.0001634427,0.0002295888,0.003186836],"study_design_scores_gemma":[0.0003641326,0.004073062,0.005266166,0.00007717566,0.0001228192,0.0007268165,0.0001561469,0.002586142,0.9591716,0.0002860748,0.02714796,0.00002192896],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9538112,0.02626988,0.008734438,0.001236157,0.0005220114,0.0002207866,0.001063234,0.0003683373,0.007774018],"genre_scores_gemma":[0.972941,0.008821174,0.006833186,0.0004259186,0.000080203,0.0002102745,0.0009124966,0.00004283743,0.009732773],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.003244017,"threshold_uncertainty_score":0.01085228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01267118987320922,"score_gpt":0.2156649613172449,"score_spread":0.2029937714440357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}