{"id":"W4212937333","doi":"10.1093/jcag/gwab049.019","title":"A20 INTESTINAL SMOOTH MUSCLE AND FIBROSTENOSIS: TARGETING NR4A1 TO MODULATE PROLIFERATIVE SIGNALLING","year":2022,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Platelet-derived growth factor receptor; Cancer research; Cell growth; Biology; Receptor; Hedgehog signaling pathway; Signal transduction; Muscle hypertrophy; Inflammation; Fibrosis; Platelet-derived growth factor; Growth factor; Medicine; Cell biology; Immunology; Internal medicine; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009740335,0.00008173122,0.0002113971,0.0001859024,0.0004234655,0.00003752482,0.0002768229,0.00002941124,0.00009531872],"category_scores_gemma":[0.0009456463,0.0000697318,0.00008690016,0.0001542487,0.00003217495,0.00008266444,0.0001030458,0.0003823857,0.000001073574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006520809,"about_ca_system_score_gemma":0.0001462393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007516901,"about_ca_topic_score_gemma":0.005469769,"domain_scores_codex":[0.9982958,0.0005850121,0.0003842498,0.0001258252,0.0003249425,0.0002841421],"domain_scores_gemma":[0.9987538,0.000119451,0.0007517066,0.00005797074,0.0001363595,0.0001807362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004728523,0.00008261677,0.4188115,0.00001784662,0.00006529698,0.00003365377,0.004092892,0.03880257,0.5282397,0.0002179157,0.008525489,0.000637621],"study_design_scores_gemma":[0.01288946,0.02484619,0.7383123,0.0007351456,0.0005490897,0.001205029,0.007310047,0.03570181,0.0920988,0.00529856,0.07963186,0.00142173],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892371,0.00000669209,0.0000763295,0.01009091,0.000394462,0.0001177627,0.00002444487,0.000003287522,0.00004896958],"genre_scores_gemma":[0.9962991,0.000002279132,0.0003312253,0.003189272,0.00008255823,0.000002771054,3.602496e-7,0.00001201408,0.00008036846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4361409,"threshold_uncertainty_score":0.3256997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01267118987320922,"score_gpt":0.2156649613172449,"score_spread":0.2029937714440357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}