{"id":"W4212974829","doi":"10.1101/2022.02.15.22270863","title":"Risk of Ocular Adverse Events with Taxane Based Chemotherapy","year":2022,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Drug-Induced Ocular Toxicity","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; University of British Columbia","funders":"","keywords":"Taxane; Medicine; Docetaxel; Hazard ratio; Internal medicine; Oncology; Adverse effect; Cabazitaxel; Paclitaxel; Retrospective cohort study; Chemotherapy; Breast cancer; Cancer; Confidence interval; Androgen deprivation therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008917,0.0004331877,0.0009106546,0.0002628734,0.00006787083,0.00000327475,0.0004141828,0.0002668796,0.001391893],"category_scores_gemma":[0.0002324087,0.000365676,0.0004253146,0.0003107421,0.0001042394,0.00002803484,0.000281909,0.001391615,0.00002506063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002307416,"about_ca_system_score_gemma":0.0005564298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002526513,"about_ca_topic_score_gemma":0.00001871829,"domain_scores_codex":[0.9970344,0.0002994226,0.0004800134,0.0007383003,0.001105112,0.0003427508],"domain_scores_gemma":[0.9971551,0.0000668596,0.0006864841,0.0017179,0.000161211,0.0002124944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007498704,0.001021272,0.980828,0.0009175781,0.00118255,0.0004142531,0.0003248303,0.00437432,0.007879712,0.000009416271,0.00011709,0.002181062],"study_design_scores_gemma":[0.009051409,0.0006265093,0.88866,0.0009228351,0.001441564,0.00003663649,0.0001901676,0.002222082,0.08185396,0.0001835892,0.0139582,0.0008530579],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944422,0.0001481839,0.001305201,0.0004673961,0.0003250454,0.001234774,0.0001363855,0.0001159473,0.001824876],"genre_scores_gemma":[0.9912184,0.00008690129,0.006854892,0.0004601333,0.0001193051,0.0001248163,0.0001916636,0.0001266641,0.0008172288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09216806,"threshold_uncertainty_score":0.9998795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01390890173172341,"score_gpt":0.2669110454505033,"score_spread":0.2530021437187799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}