{"id":"W4213020415","doi":"10.14309/ctg.0000000000000466","title":"Relationship Between Hepatic Gene Expression, Intestinal Microbiota, and Inferred Functional Metagenomic Analysis in NAFLD","year":2022,"lang":"en","type":"article","venue":"Clinical and Translational Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Wilson Centre; Public Health Ontario; University Health Network; University of Toronto; Toronto General Hospital; Canada Research Chairs","funders":"Canadian Institutes of Health Research","keywords":"Metagenomics; Medicine; Gene; Computational biology; Functional analysis; Gene expression; Bioinformatics; Internal medicine; Gastroenterology; Microbiology; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005473857,0.0001240629,0.0002808648,0.0001588007,0.0001691783,0.000009353631,0.00007848061,0.00009467635,0.00007418047],"category_scores_gemma":[0.00005277533,0.0001270668,0.000114208,0.0001301221,0.0001924026,0.000005356327,0.0001022324,0.0003027004,0.000001507958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006222328,"about_ca_system_score_gemma":0.00005412335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001539425,"about_ca_topic_score_gemma":0.0001233261,"domain_scores_codex":[0.9983584,0.0003888773,0.000543361,0.000431959,0.00007170127,0.0002057],"domain_scores_gemma":[0.9994768,0.0001673542,0.0001039646,0.0001229272,0.00002748557,0.0001014736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00039414,0.00008540433,0.9830518,0.000008619167,0.0001024135,0.000002140858,0.00002677122,0.0002926146,0.01582355,0.00004616063,0.00007948463,0.00008686898],"study_design_scores_gemma":[0.001412765,0.0003853852,0.9969701,0.000002101035,0.0001398805,0.00003849922,0.00001336947,0.00009045882,0.00007199891,0.0003401828,0.0004581173,0.00007714039],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937291,0.0003117647,0.004612687,0.001012692,0.00007281793,0.0001270851,0.0001172703,0.000005492887,0.0000111382],"genre_scores_gemma":[0.9961334,0.00002333276,0.00203872,0.000562021,0.0001017772,0.00002202497,0.001052113,0.000008913538,0.00005766717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01575155,"threshold_uncertainty_score":0.5181633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04536379695633182,"score_gpt":0.3112626388917772,"score_spread":0.2658988419354454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}