{"id":"W4213037617","doi":"10.1002/ski2.99","title":"Break on Through: The Role of Innate Immunity and Barrier Defence in Atopic Dermatitis and Psoriasis","year":2022,"lang":"en","type":"review","venue":"Skin Health and Disease","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"Irish Research Council; Science Foundation Ireland; Else Kröner-Fresenius-Stiftung; National Children's Research Centre","keywords":"Psoriasis; Atopic dermatitis; Innate immune system; Immunology; Skin barrier; Immunity; Medicine; Dermatology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001816409,0.000226456,0.0009057908,0.000109162,0.0002304072,0.00001183615,0.00008894255,0.00008834487,0.00008393591],"category_scores_gemma":[0.000443323,0.0001553463,0.0001004335,0.0001798302,0.0002523843,0.00005172141,0.0001245887,0.0003753041,0.000001538378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003401696,"about_ca_system_score_gemma":0.0009475634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003004796,"about_ca_topic_score_gemma":0.00002062856,"domain_scores_codex":[0.9983441,0.0005236784,0.0004517084,0.0002756454,0.0001600054,0.0002449007],"domain_scores_gemma":[0.9983792,0.0004785072,0.0001963008,0.0003497799,0.00001318245,0.0005830492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000119234,0.0001828383,0.02315179,0.03507613,0.00006258291,0.0001058028,0.0009635292,9.140933e-8,3.698367e-9,0.001258783,0.00130705,0.9377722],"study_design_scores_gemma":[0.0007817646,0.00009704102,0.03548894,0.00450604,0.0003621736,0.0001610866,0.0005283097,0.000007229988,1.23197e-7,0.003690373,0.9542043,0.000172571],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006420181,0.9912413,3.485561e-7,0.0006150695,0.00006466428,0.0008114448,0.0002524051,0.00001172065,0.0005828333],"genre_scores_gemma":[0.04274908,0.9542574,0.000009603918,0.002648905,0.00002754762,0.0001516839,0.000120137,0.00001516987,0.00002047094],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9528973,"threshold_uncertainty_score":0.6334838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02856114600319105,"score_gpt":0.3357375577099518,"score_spread":0.3071764117067607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}