{"id":"W4213055357","doi":"10.1038/s41388-022-02223-y","title":"TSPAN6 is a suppressor of Ras-driven cancer","year":2022,"lang":"en","type":"article","venue":"Oncogene","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Health and Medical Research Council; Medical Research Council; La Trobe University; Cancer Council Victoria; Invest Northern Ireland","keywords":"Biology; Suppressor; Carcinogenesis; Cancer; Cancer research; Tumor suppressor gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006518133,0.0002926836,0.0001149421,0.0002753224,0.0001646173,0.0001321948,0.000138242,0.0001715568,0.002157022],"category_scores_gemma":[0.00007276817,0.00008067162,0.0001499871,0.0001420155,0.0001599347,0.00006113027,0.0001696157,0.0003215785,0.0005887224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002165447,"about_ca_system_score_gemma":0.0001434139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004284155,"about_ca_topic_score_gemma":0.000738991,"domain_scores_codex":[0.9999229,0.00001256024,0.0000057935,0.00001459021,0.00003424814,0.000009964922],"domain_scores_gemma":[0.9999235,0.000007481166,0.00002284979,0.000006212843,0.000007459899,0.00003241434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007002449,0.00001241366,0.0006047241,0.00002411117,0.000008598284,0.0003067678,0.000004880739,0.00008822562,0.9970016,0.0001981349,0.0001300914,0.001550393],"study_design_scores_gemma":[0.00003077653,0.0002499924,0.02301862,0.000008035239,0.00003751153,0.008506969,0.00002940831,0.003155033,0.9471409,0.0002830959,0.0175314,0.000008157014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920407,0.001341183,0.003041,0.0001521878,0.00004258997,0.00001574591,0.001212635,0.0001657184,0.001988321],"genre_scores_gemma":[0.9913373,0.0005258265,0.001375204,0.00004397761,0.00001041011,0.00001043702,0.001548941,0.00001915036,0.005128738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002157022,"threshold_uncertainty_score":0.007215977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01660922445908601,"score_gpt":0.2870573461213838,"score_spread":0.2704481216622978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}