{"id":"W4213081776","doi":"10.1093/jcag/gwab049.051","title":"A52 GUT-INNERVATING TRPV1+ NEURONS DRIVE CHRONIC VISCERAL PAIN VIA MICROGLIAL P2Y12 RECEPTOR","year":2022,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Microglia; TRPV1; Nociceptor; Medicine; Visceral pain; Sensitization; Spinal cord; Colitis; Inflammatory bowel disease; Inflammation; Chronic pain; Neuroscience; Immunology; Receptor; Nociception; Pathology; Internal medicine; Disease; Biology; Transient receptor potential channel","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001334957,0.0003426207,0.0003334781,0.0001536224,0.0001931334,0.0002719124,0.0002005051,0.0003346296,0.003147734],"category_scores_gemma":[0.0001111604,0.0001418718,0.0002916571,0.0001290312,0.0002645676,0.0002274507,0.0001691499,0.0006616637,0.0005350551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001992559,"about_ca_system_score_gemma":0.0002016124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003659938,"about_ca_topic_score_gemma":0.0005982823,"domain_scores_codex":[0.9998242,0.00002422068,0.00001475774,0.00003630563,0.00003316214,0.00006738645],"domain_scores_gemma":[0.9999436,0.000008945207,0.00001729598,0.000007929641,0.00000719907,0.00001508727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002108999,0.00004060516,0.0001114403,0.00005090974,0.00000424229,0.00003699689,0.000009656932,0.00002668275,0.9986237,0.00005406233,0.0000443465,0.0007863368],"study_design_scores_gemma":[0.0001034269,0.002294288,0.009932856,0.00002345573,0.00004597896,0.0005890643,0.00009945217,0.001118287,0.9833047,0.0001496763,0.002329285,0.000009582723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938993,0.001750963,0.002357446,0.0001857718,0.00005335415,0.00003929033,0.0002623427,0.00007782575,0.001373669],"genre_scores_gemma":[0.9954818,0.0008748604,0.001193081,0.00008053741,0.00002020878,0.00006737783,0.0001580942,0.000008929122,0.002115034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003147734,"threshold_uncertainty_score":0.01053017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007271323647929745,"score_gpt":0.2113609481954511,"score_spread":0.2040896245475214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}