{"id":"W4213100783","doi":"10.1371/journal.pgen.1010034","title":"MxB inhibits long interspersed element type 1 retrotransposition","year":2022,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"Canadian Institutes of Health Research; Chinese Academy of Medical Sciences; Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China","keywords":"Retrotransposon; Biology; Transposable element; Stress granule; Genetics; Gene knockdown; Cell biology; RNA interference; Cytoplasm; Gene; Genome; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001494889,0.0003645001,0.0003082223,0.0001794795,0.0001244439,0.0002163474,0.0001707959,0.0002689681,0.001418662],"category_scores_gemma":[0.0001077453,0.0001232882,0.000205124,0.00009070028,0.0001919465,0.0001154819,0.0002057251,0.0006762568,0.0003480195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001400601,"about_ca_system_score_gemma":0.000142445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001971796,"about_ca_topic_score_gemma":0.0004898562,"domain_scores_codex":[0.9998801,0.0000303545,0.00001210474,0.00002076421,0.00003033537,0.00002619298],"domain_scores_gemma":[0.9999244,0.00001592774,0.00002186535,0.000008370243,0.000004781193,0.00002471731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001207501,0.00006414441,0.0001054683,0.00003099213,0.000004809262,0.00001672505,0.000007362428,0.00002884083,0.9980438,0.0001148293,0.00007359947,0.00138874],"study_design_scores_gemma":[0.00004907951,0.0009378851,0.003969548,0.00000728377,0.000009565519,0.0001474279,0.00001235982,0.0007462665,0.9897671,0.00006606411,0.004284467,0.000002972694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884362,0.004956804,0.003291164,0.0002925203,0.00009625455,0.00005300616,0.0004008774,0.0003028317,0.002170289],"genre_scores_gemma":[0.991486,0.001790533,0.002419652,0.00007765891,0.00002706255,0.00006358563,0.0004887339,0.00002959983,0.00361708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001418662,"threshold_uncertainty_score":0.004745841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02578207138766301,"score_gpt":0.209602192044155,"score_spread":0.183820120656492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}