{"id":"W4213100783","doi":"10.1371/journal.pgen.1010034","title":"MxB inhibits long interspersed element type 1 retrotransposition","year":2022,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"Canadian Institutes of Health Research; Chinese Academy of Medical Sciences; Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China","keywords":"Retrotransposon; Biology; Transposable element; Stress granule; Genetics; Gene knockdown; Cell biology; RNA interference; Cytoplasm; Gene; Genome; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00005651689,0.00007658228,0.00007133054,0.000008288685,0.0002793855,0.00002237053,0.0001454624,0.00002482332,0.003385019],"category_scores_gemma":[0.000005735337,0.00003742599,0.00004390996,0.0002639471,0.00001447618,0.0000159396,0.00008496275,0.00009178225,0.00004093406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004542927,"about_ca_system_score_gemma":0.00000816473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007347501,"about_ca_topic_score_gemma":0.0001331718,"domain_scores_codex":[0.9992384,0.00005512147,0.0001351823,0.0001787818,0.0002328763,0.0001596905],"domain_scores_gemma":[0.9997905,0.00002327263,0.00003858639,0.00004673296,0.00004696241,0.0000539006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002863027,0.0002967183,0.01082647,0.000004328819,0.00002695941,0.000004715842,0.0003467146,0.0003270579,0.9799445,0.0001138468,0.0003168135,0.007763236],"study_design_scores_gemma":[0.001162443,0.006054475,0.152973,0.00004709331,0.0002452011,0.00005561785,0.002475738,0.01321775,0.7166456,0.002004037,0.103871,0.001248018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973759,0.0001749952,0.000003959125,0.001210242,0.0001582181,0.0001814169,0.00006983044,0.00004002174,0.0007854188],"genre_scores_gemma":[0.9990214,0.00003446901,0.0001074847,0.0002884616,0.0001547815,0.00002668828,0.0001923136,0.000001008384,0.0001733917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2632989,"threshold_uncertainty_score":0.997526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02578207138766301,"score_gpt":0.209602192044155,"score_spread":0.183820120656492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}