{"id":"W4213104442","doi":"10.1093/cid/ciac152","title":"The Effect of Regularly Dosed Acetaminophen vs No Acetaminophen on Renal Function in <i>Plasmodium knowlesi</i> Malaria (PACKNOW): A Randomized, Controlled Trial","year":2022,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Malaria Research and Control","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; National Institutes of Health; Drugs for Neglected Diseases initiative; Australian Government; Menzies School of Health Research; Wellcome Trust; World Health Organization; National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; Pfizer","keywords":"Medicine; Acetaminophen; Creatinine; Plasmodium knowlesi; Renal function; Hemolysis; Acute kidney injury; Malaria; Internal medicine; Gastroenterology; Surgery; Plasmodium falciparum; Anesthesia; Immunology; Plasmodium vivax","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.008272105,0.0004211572,0.003196839,0.0002706329,0.0004364925,0.000143295,0.0003409513,0.0002108164,0.0008017794],"category_scores_gemma":[0.02077794,0.0002535087,0.002054301,0.0004654202,0.0006295841,0.0001611454,0.0002260373,0.001257352,0.0001134483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002121357,"about_ca_system_score_gemma":0.0005581397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004155576,"about_ca_topic_score_gemma":0.00002551649,"domain_scores_codex":[0.9873591,0.008247247,0.001929237,0.0006822468,0.001136745,0.0006454457],"domain_scores_gemma":[0.9775785,0.02008746,0.0006908788,0.000900579,0.0002792851,0.0004633602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9810767,0.002060813,0.006206604,0.00008860756,0.001348547,0.00006975587,0.00001401585,0.0001012594,0.0001064174,0.001101513,0.00288682,0.004938977],"study_design_scores_gemma":[0.9499143,0.02929877,0.01366255,0.0001156258,0.0018553,0.000005972413,0.00002327886,0.002065556,0.00003326248,0.0006065323,0.002195961,0.0002228439],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9685535,0.002257247,0.00007288465,0.002899298,0.003903601,0.0176865,0.00004688369,0.0001621229,0.004417908],"genre_scores_gemma":[0.9887453,0.000377625,0.000002285767,0.0005776811,0.001073811,0.006113185,0.00006537776,0.00004861909,0.002996172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03116233,"threshold_uncertainty_score":0.9999917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01178371248743956,"score_gpt":0.3029783660948208,"score_spread":0.2911946536073813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}