{"id":"W4213104442","doi":"10.1093/cid/ciac152","title":"The Effect of Regularly Dosed Acetaminophen vs No Acetaminophen on Renal Function in <i>Plasmodium knowlesi</i> Malaria (PACKNOW): A Randomized, Controlled Trial","year":2022,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Malaria Research and Control","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; National Institutes of Health; Drugs for Neglected Diseases initiative; Australian Government; Menzies School of Health Research; Wellcome Trust; World Health Organization; National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; Pfizer","keywords":"Medicine; Acetaminophen; Creatinine; Plasmodium knowlesi; Renal function; Hemolysis; Acute kidney injury; Malaria; Internal medicine; Gastroenterology; Surgery; Plasmodium falciparum; Anesthesia; Immunology; Plasmodium vivax","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001611726,0.001031905,0.003425101,0.0004104681,0.0004373888,0.001024168,0.0008567827,0.002089363,0.005379866],"category_scores_gemma":[0.002737372,0.000540994,0.002668085,0.0004497279,0.0007856633,0.001037352,0.0003928095,0.002137024,0.0004076342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006165431,"about_ca_system_score_gemma":0.0008568036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000989084,"about_ca_topic_score_gemma":0.001591698,"domain_scores_codex":[0.9991391,0.0004688274,0.00009641321,0.0001361165,0.00006021876,0.00009938465],"domain_scores_gemma":[0.9982034,0.0006943886,0.0005691348,0.00008284571,0.0001101123,0.0003400868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9852942,0.002632326,0.0004988788,0.001766735,0.001491432,0.00002395039,0.00002156307,0.0001011427,0.0004248924,0.00004779835,0.0002890651,0.007408023],"study_design_scores_gemma":[0.9584414,0.03772768,0.001616224,0.0001420071,0.001319881,0.0000196,0.00001857545,0.0002253251,0.0001463494,0.00008072555,0.0002510531,0.0000110668],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756231,0.0161629,0.0004613452,0.0009342514,0.001001354,0.00335924,0.0008892103,0.00009722716,0.001471433],"genre_scores_gemma":[0.9854171,0.006401104,0.001177777,0.001411919,0.0007235117,0.003241539,0.0005761684,0.00001170529,0.001039296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005379866,"threshold_uncertainty_score":0.01799738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01178371248743956,"score_gpt":0.3029783660948208,"score_spread":0.2911946536073813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}