{"id":"W4213108482","doi":"10.26508/lsa.202101192","title":"Muscle stem cell polarity requires QKI-mediated alternative splicing of Integrin Alpha-7 (Itga7)","year":2022,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cell polarity; Cell biology; Alternative splicing; Stem cell; Progenitor cell; Population; RNA splicing; Genetics; Cell; Gene isoform; RNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001527447,0.0003903701,0.0001855581,0.0001952913,0.0001745004,0.0004228067,0.0001946655,0.0002513226,0.0009491936],"category_scores_gemma":[0.0001272135,0.0001959168,0.0002679469,0.00009574367,0.0003787298,0.0002264085,0.0003535454,0.0004839224,0.0006753494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002949295,"about_ca_system_score_gemma":0.000210236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003162017,"about_ca_topic_score_gemma":0.0006562796,"domain_scores_codex":[0.9997873,0.00002204752,0.00001673644,0.00005149683,0.00007402197,0.00004845779],"domain_scores_gemma":[0.9998298,0.00002055534,0.00007397516,0.00001769222,0.00002197658,0.00003602927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001325424,0.000002383514,0.0002032617,0.000006316609,0.000001281376,0.00003218082,0.000007779809,0.00002824218,0.9991261,0.0001281713,0.000009539097,0.0004414701],"study_design_scores_gemma":[0.000007092729,0.000100939,0.006673713,0.000005598881,0.0000129777,0.0003235767,0.00004426143,0.001251349,0.9897714,0.0001130535,0.001691482,0.000004428606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841328,0.0008851806,0.0122809,0.0001078992,0.00003476961,0.00002442025,0.000200678,0.0001985339,0.002134902],"genre_scores_gemma":[0.9927569,0.0003888631,0.003306649,0.00006277536,0.00001273954,0.00002154244,0.0003790821,0.0000533222,0.003018097],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009491936,"threshold_uncertainty_score":0.003175378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02268319683293726,"score_gpt":0.2870651139061244,"score_spread":0.2643819170731872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}