{"id":"W4213108482","doi":"10.26508/lsa.202101192","title":"Muscle stem cell polarity requires QKI-mediated alternative splicing of Integrin Alpha-7 (Itga7)","year":2022,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cell polarity; Cell biology; Alternative splicing; Stem cell; Progenitor cell; Population; RNA splicing; Genetics; Cell; Gene isoform; RNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00102767,0.0001229637,0.0001536109,0.00006900332,0.0003559665,0.00003625314,0.000994895,0.00003577298,0.00004376426],"category_scores_gemma":[0.000188877,0.0001187108,0.00006422373,0.0005603881,0.0004319069,0.00002382261,0.0006734245,0.000238007,0.000009778364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005919396,"about_ca_system_score_gemma":0.0004332403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004287898,"about_ca_topic_score_gemma":0.00003637936,"domain_scores_codex":[0.998009,0.00009434599,0.0002528496,0.000522419,0.0006471348,0.0004742638],"domain_scores_gemma":[0.999006,0.00003492061,0.0001600033,0.0004431708,0.0001481531,0.0002077115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004203695,0.00005871274,0.003941228,0.00001545929,0.000006912386,0.000005169182,0.0001698995,0.0004408793,0.9938625,0.00009327796,0.0002520294,0.001111968],"study_design_scores_gemma":[0.0004958769,0.0005407324,0.01016898,0.00002266203,0.000004127701,0.000004329497,0.001306042,0.004146338,0.9758363,0.0000518767,0.007187784,0.000234896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972309,0.000553909,0.0003681205,0.0003135494,0.0001846885,0.0001825526,0.00004391352,0.00001123701,0.001111141],"genre_scores_gemma":[0.9971091,0.0001609926,0.0003879141,0.0004153323,0.0000793754,0.00002567512,0.00001306652,0.00001154946,0.001796957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01802607,"threshold_uncertainty_score":0.4840887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02268319683293726,"score_gpt":0.2870651139061244,"score_spread":0.2643819170731872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}