{"id":"W4213164681","doi":"10.3390/cancers14041004","title":"Clinical Management of Prostate Cancer in High-Risk Genetic Mutation Carriers","year":2022,"lang":"en","type":"review","venue":"Cancers","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Prostate cancer; Medicine; Germline; Germline mutation; Disease; Cancer; Prostate; Management of prostate cancer; Oncology; Internal medicine; Mutation; Genetics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001238438,0.0006117147,0.001266827,0.002639079,0.0002618418,0.0009723225,0.0007969642,0.001011999,0.002505486],"category_scores_gemma":[0.004431112,0.0001915637,0.001102199,0.002124774,0.0003566205,0.0007856438,0.0004755383,0.0007520814,0.0004726663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008208851,"about_ca_system_score_gemma":0.001982529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002030525,"about_ca_topic_score_gemma":0.004299566,"domain_scores_codex":[0.9991031,0.0003271062,0.0002168125,0.0000869115,0.0002272754,0.00003888565],"domain_scores_gemma":[0.9983071,0.001113648,0.0002989703,0.00002134959,0.000226964,0.00003201552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001027648,0.00003234609,0.000840019,0.1883748,0.0005782772,0.0003700365,0.0001564003,0.0003774243,0.0004995493,0.001351852,0.02336167,0.7839549],"study_design_scores_gemma":[0.00008447076,0.0002047837,0.005992112,0.3166229,0.002984612,0.006884784,0.0004453267,0.0002411444,0.0006214876,0.002810981,0.6630536,0.00005382911],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001067164,0.9991378,0.00005009349,0.0002556451,0.00008831943,0.000005730933,0.00001594489,0.000002098644,0.0003376314],"genre_scores_gemma":[0.00135558,0.9980361,0.0001694499,0.000238568,0.0000838374,0.000008413426,0.00002620219,8.857265e-7,0.00008095054],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002639079,"threshold_uncertainty_score":0.008381665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05055452049977077,"score_gpt":0.3891375134141815,"score_spread":0.3385829929144107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}