{"id":"W4213166923","doi":"10.1101/2022.02.14.480455","title":"Diverse innate immune factors protect yeast from lethal viral pathogenesis","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Plant and Fungal Interactions Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Saccharomyces cerevisiae; Yeast; Innate immune system; Virology; RNA; RNA interference; Virus; Genetics; Computational biology; Gene; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001018783,0.0003667033,0.0001907917,0.0002023686,0.00009134527,0.000299037,0.0001611825,0.0001640941,0.0007779499],"category_scores_gemma":[0.00006515063,0.00008195019,0.0002346078,0.0000904172,0.0001618159,0.0001224966,0.0002326391,0.000306345,0.0003501559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002116746,"about_ca_system_score_gemma":0.0001931848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003397724,"about_ca_topic_score_gemma":0.0003491466,"domain_scores_codex":[0.9999402,0.0000115825,0.000007132287,0.00001396666,0.0000125635,0.00001467755],"domain_scores_gemma":[0.9999094,0.00001506864,0.00002481619,0.00001203326,0.00001283583,0.00002578027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008675594,0.00001494792,0.000190565,0.00002609403,0.000003406568,0.00003253791,0.000005634529,0.00003493266,0.998571,0.00006432604,0.0000241346,0.0009455631],"study_design_scores_gemma":[0.00001971961,0.000284756,0.00362023,0.000008668734,0.00001144742,0.0001840907,0.00004451046,0.0005542369,0.9932885,0.0001225528,0.001856044,0.000005153158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907632,0.003225548,0.003877703,0.0001100404,0.00002930308,0.00002709686,0.0005361406,0.0002302638,0.001200688],"genre_scores_gemma":[0.9953746,0.0006524467,0.001925585,0.00006557832,0.000007765038,0.00001808729,0.0006922234,0.00002169424,0.001242169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007779499,"threshold_uncertainty_score":0.002602518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01941154201707878,"score_gpt":0.2459191541161171,"score_spread":0.2265076120990384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}