{"id":"W4213166923","doi":"10.1101/2022.02.14.480455","title":"Diverse innate immune factors protect yeast from lethal viral pathogenesis","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Plant and Fungal Interactions Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Saccharomyces cerevisiae; Yeast; Innate immune system; Virology; RNA; RNA interference; Virus; Genetics; Computational biology; Gene; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003349711,0.0005068677,0.0004139075,0.0002159021,0.0003089128,0.0001669076,0.0008338836,0.000530965,0.0004523128],"category_scores_gemma":[0.0002021288,0.0005375748,0.000300922,0.0002179852,0.0001037221,0.000013839,0.001865972,0.001021239,0.00006567814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001592866,"about_ca_system_score_gemma":0.0004414772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006486921,"about_ca_topic_score_gemma":0.00001185665,"domain_scores_codex":[0.9972878,0.0002856081,0.0004004328,0.001059143,0.0004285105,0.0005385699],"domain_scores_gemma":[0.9981141,0.00002504351,0.0002617004,0.00115711,0.0002367342,0.0002052979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001543987,0.0001259396,0.009407468,0.00005010334,0.0002977268,0.00008771563,0.000007265284,0.00005704933,0.9893456,0.00001074548,0.0004522164,0.000003847671],"study_design_scores_gemma":[0.000373179,0.0001261613,0.09441064,0.00005950997,0.00007187336,3.738455e-8,0.00002075654,0.00008937849,0.8764534,6.344265e-7,0.02766686,0.0007275779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915062,0.001077213,0.0002349982,0.00003856646,0.001224295,0.0006358975,0.005162585,0.00009484382,0.00002541876],"genre_scores_gemma":[0.9980213,0.0002968151,0.0005342243,0.00003843379,0.0005537032,0.000324526,0.00005383417,0.0001081304,0.00006903542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1128921,"threshold_uncertainty_score":0.9997076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01941154201707878,"score_gpt":0.2459191541161171,"score_spread":0.2265076120990384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}