{"id":"W4213177367","doi":"10.1016/j.urology.2022.02.006","title":"Immunohistochemical Screening of Upper Tract Urothelial Carcinomas for Lynch Syndrome Diagnostics: A Systematic Review","year":2022,"lang":"en","type":"review","venue":"Urology","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Danish Cancer Society Research Center; Kræftens Bekæmpelse","keywords":"Medicine; Lynch syndrome; Urothelial carcinoma; Immunohistochemistry; Urothelial cancer; Pathology; Urology; Oncology; Internal medicine; DNA mismatch repair; Cancer; Bladder cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006485691,0.001274085,0.007709018,0.005492605,0.0004127159,0.001705796,0.001656473,0.001606811,0.002842714],"category_scores_gemma":[0.02824569,0.0008389334,0.008600288,0.005543134,0.0006522966,0.00152097,0.0009266426,0.0006556719,0.0002541673],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001586221,"about_ca_system_score_gemma":0.003684778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004006959,"about_ca_topic_score_gemma":0.01156473,"domain_scores_codex":[0.9947231,0.001776706,0.001975544,0.0005542983,0.0007906257,0.0001797982],"domain_scores_gemma":[0.9706495,0.02107057,0.005391175,0.0004336552,0.002221325,0.0002338218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0007078746,0.00002070251,0.005096233,0.9191799,0.04521903,0.0001318301,0.00009218616,0.0001103931,0.0003112553,0.00009463591,0.00114313,0.02789292],"study_design_scores_gemma":[0.0007034601,0.0005117737,0.02186859,0.5696026,0.3945089,0.000816197,0.0002151023,0.000149124,0.0003615195,0.0002526929,0.01095887,0.00005117027],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001932207,0.9973472,0.00007511532,0.0001197508,0.00006446195,0.00008082588,0.0002396485,0.000004543094,0.0001362393],"genre_scores_gemma":[0.04731411,0.9507616,0.0005629635,0.0005290553,0.0001438461,0.0002616216,0.0003202549,0.000006696645,0.00009987126],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007709018,"threshold_uncertainty_score":0.03429997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05495725899504455,"score_gpt":0.3474734313799532,"score_spread":0.2925161723849087,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}